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Metastatic Conditioning of Myeloid Cells at a Subcutaneous Synthetic Niche Reflects Disease Progression and Predicts Therapeutic Outcomes.
Oakes RS, Bushnell GG, Orbach SM, Kandagatla P, Zhang Y, Morris AH, Hall MS, LaFaire P, Decker JT, Hartfield RM, Brooks MD, Wicha MS, Jeruss JS, Shea LD. Oakes RS, et al. Among authors: orbach sm. Cancer Res. 2020 Feb 1;80(3):602-612. doi: 10.1158/0008-5472.CAN-19-1932. Epub 2019 Oct 29. Cancer Res. 2020. PMID: 31662327 Free PMC article.
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Kemp SB, Steele NG, Carpenter ES, Donahue KL, Bushnell GG, Morris AH, The S, Orbach SM, Sirihorachai VR, Nwosu ZC, Espinoza C, Lima F, Brown K, Girgis AA, Gunchick V, Zhang Y, Lyssiotis CA, Frankel TL, Bednar F, Rao A, Sahai V, Shea LD, Crawford HC, Pasca di Magliano M. Kemp SB, et al. Among authors: orbach sm. Life Sci Alliance. 2021 Mar 29;4(6):e202000935. doi: 10.26508/lsa.202000935. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33782087 Free PMC article.
Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.
Podojil JR, Cogswell AC, Chiang MY, Eaton V, Ifergan I, Neef T, Xu D, Meghani KA, Yu Y, Orbach SM, Murthy T, Boyne MT, Elhofy A, Shea LD, Meeks JJ, Miller SD. Podojil JR, et al. Among authors: orbach sm. Front Immunol. 2022 Aug 18;13:887649. doi: 10.3389/fimmu.2022.887649. eCollection 2022. Front Immunol. 2022. PMID: 36059473 Free PMC article.
19 results