Diekman BO - Search Results

1

Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis.

Copp ME, Chubinskaya S, Bracey DN, Shine J, Sessions G, Loeser RF, Diekman BO. Copp ME, et al. Among authors: diekman bo. Aging Cell. 2022 Sep;21(9):e13698. doi: 10.1111/acel.13698. Epub 2022 Aug 22. Aging Cell. 2022. PMID: 35996812 Free PMC article.

2

Ageing and the pathogenesis of osteoarthritis.

Loeser RF, Collins JA, Diekman BO. Loeser RF, et al. Among authors: diekman bo. Nat Rev Rheumatol. 2016 Jul;12(7):412-20. doi: 10.1038/nrrheum.2016.65. Epub 2016 May 19. Nat Rev Rheumatol. 2016. PMID: 27192932 Free PMC article. Review.

3

Targeting aging for disease modification in osteoarthritis.

Collins JA, Diekman BO, Loeser RF. Collins JA, et al. Among authors: diekman bo. Curr Opin Rheumatol. 2018 Jan;30(1):101-107. doi: 10.1097/BOR.0000000000000456. Curr Opin Rheumatol. 2018. PMID: 28957964 Free PMC article. Review.

4

Expression of p16^INK^4a is a biomarker of chondrocyte aging but does not cause osteoarthritis.

Diekman BO, Sessions GA, Collins JA, Knecht AK, Strum SL, Mitin NK, Carlson CS, Loeser RF, Sharpless NE. Diekman BO, et al. Aging Cell. 2018 Aug;17(4):e12771. doi: 10.1111/acel.12771. Epub 2018 May 9. Aging Cell. 2018. PMID: 29744983 Free PMC article.

5

Does Joint Injury Make Young Joints Old?

Diekman BO, Collins JA, Loeser RF. Diekman BO, et al. J Am Acad Orthop Surg. 2018 Nov 1;26(21):e455-e456. doi: 10.5435/JAAOS-D-18-00394. J Am Acad Orthop Surg. 2018. PMID: 30134310 Free PMC article. No abstract available.

6

Cells exhibiting strong p16^INK4a promoter activation in vivo display features of senescence.

Liu JY, Souroullas GP, Diekman BO, Krishnamurthy J, Hall BM, Sorrentino JA, Parker JS, Sessions GA, Gudkov AV, Sharpless NE. Liu JY, et al. Among authors: diekman bo. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2603-2611. doi: 10.1073/pnas.1818313116. Epub 2019 Jan 25. Proc Natl Acad Sci U S A. 2019. PMID: 30683717 Free PMC article.

7

Controlled induction and targeted elimination of p16^INK4a-expressing chondrocytes in cartilage explant culture.

Sessions GA, Copp ME, Liu JY, Sinkler MA, D'Costa S, Diekman BO. Sessions GA, et al. Among authors: diekman bo. FASEB J. 2019 Nov;33(11):12364-12373. doi: 10.1096/fj.201900815RR. Epub 2019 Aug 13. FASEB J. 2019. PMID: 31408372 Free PMC article.

8

Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation.

Tessier S, Doolittle AC, Sao K, Rotty JD, Bear JE, Ulici V, Loeser RF, Shapiro IM, Diekman BO, Risbud MV. Tessier S, et al. Among authors: diekman bo. JCI Insight. 2020 Feb 27;5(4):e131382. doi: 10.1172/jci.insight.131382. JCI Insight. 2020. PMID: 31961823 Free PMC article.

9

Deletion of JNK Enhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice.

Loeser RF, Kelley KL, Armstrong A, Collins JA, Diekman BO, Carlson CS. Loeser RF, et al. Among authors: diekman bo. Arthritis Rheumatol. 2020 Oct;72(10):1679-1688. doi: 10.1002/art.41312. Epub 2020 Aug 26. Arthritis Rheumatol. 2020. PMID: 32418287 Free PMC article.

10

Mechanisms and therapeutic implications of cellular senescence in osteoarthritis.

Coryell PR, Diekman BO, Loeser RF. Coryell PR, et al. Among authors: diekman bo. Nat Rev Rheumatol. 2021 Jan;17(1):47-57. doi: 10.1038/s41584-020-00533-7. Epub 2020 Nov 18. Nat Rev Rheumatol. 2021. PMID: 33208917 Free PMC article. Review.

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