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The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis.
Jarr KU, Ye J, Kojima Y, Ye Z, Gao H, Schmid S, Luo L, Baylis RA, Lotfi M, Lopez N, Eberhard AV, Smith BR, Weissman IL, Maegdefessel L, Leeper NJ. Jarr KU, et al. Among authors: baylis ra. Nat Cardiovasc Res. 2022 Mar;1(3):253-262. doi: 10.1038/s44161-022-00023-x. Epub 2022 Mar 7. Nat Cardiovasc Res. 2022. PMID: 35990913 Free PMC article.
Cancer Incidence After Diagnosis of Abdominal Aortic Aneurysm.
Luo L, Haas AM, Bell CF, Baylis RA, Adkar SS, Fu C, Angelov I, Giordano SH, Klarin D, Leeper NJ, Nead KT. Luo L, et al. Among authors: baylis ra. Arterioscler Thromb Vasc Biol. 2024 May 23. doi: 10.1161/ATVBAHA.123.320543. Online ahead of print. Arterioscler Thromb Vasc Biol. 2024. PMID: 38779853
Endothelial OCT4 is atheroprotective by preventing metabolic and phenotypic dysfunction.
Shin J, Tkachenko S, Chaklader M, Pletz C, Singh K, Bulut GB, Han YM, Mitchell K, Baylis RA, Kuzmin AA, Hu B, Lathia JD, Stenina-Adognravi O, Podrez E, Byzova TV, Owens GK, Cherepanova OA. Shin J, et al. Among authors: baylis ra. Cardiovasc Res. 2022 Aug 24;118(11):2458-2477. doi: 10.1093/cvr/cvac036. Cardiovasc Res. 2022. PMID: 35325071 Free PMC article.
Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice.
Gomez D, Baylis RA, Durgin BG, Newman AAC, Alencar GF, Mahan S, St Hilaire C, Müller W, Waisman A, Francis SE, Pinteaux E, Randolph GJ, Gram H, Owens GK. Gomez D, et al. Among authors: baylis ra. Nat Med. 2018 Sep;24(9):1418-1429. doi: 10.1038/s41591-018-0124-5. Epub 2018 Jul 23. Nat Med. 2018. PMID: 30038218 Free PMC article.
Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Alencar GF, Owsiany KM, Karnewar S, Sukhavasi K, Mocci G, Nguyen AT, Williams CM, Shamsuzzaman S, Mokry M, Henderson CA, Haskins R, Baylis RA, Finn AV, McNamara CA, Zunder ER, Venkata V, Pasterkamp G, Björkegren J, Bekiranov S, Owens GK. Alencar GF, et al. Among authors: baylis ra. Circulation. 2020 Nov 24;142(21):2045-2059. doi: 10.1161/CIRCULATIONAHA.120.046672. Epub 2020 Jul 17. Circulation. 2020. PMID: 32674599 Free PMC article.
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