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Dietary methionine starvation impairs acute myeloid leukemia progression.
Cunningham A, Erdem A, Alshamleh I, Geugien M, Pruis M, Pereira-Martins DA, van den Heuvel FAJ, Wierenga ATJ, Ten Berge H, Dennebos R, van den Boom V, Hogeling SM, Weinhäuser I, Knops R, de Blaauw P, Heiner-Fokkema MR, Woolthuis C, Günther UL, Rego EM, Martens JHA, Jansen JH, Schwalbe H, Huls G, Schuringa JJ. Cunningham A, et al. Among authors: van den heuvel faj. Blood. 2022 Nov 10;140(19):2037-2052. doi: 10.1182/blood.2022017575. Blood. 2022. PMID: 35984907 Free article.
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.
Erdem A, Marin S, Pereira-Martins DA, Cortés R, Cunningham A, Pruis MG, de Boer B, van den Heuvel FAJ, Geugien M, Wierenga ATJ, Brouwers-Vos AZ, Rego EM, Huls G, Cascante M, Schuringa JJ. Erdem A, et al. Among authors: van den heuvel faj. Nat Commun. 2022 Mar 1;13(1):1105. doi: 10.1038/s41467-022-28737-3. Nat Commun. 2022. PMID: 35232995 Free PMC article.
Glutathione and antioxidant enzymes serve complementary roles in protecting activated hepatic stellate cells against hydrogen peroxide-induced cell death.
Dunning S, Ur Rehman A, Tiebosch MH, Hannivoort RA, Haijer FW, Woudenberg J, van den Heuvel FA, Buist-Homan M, Faber KN, Moshage H. Dunning S, et al. Biochim Biophys Acta. 2013 Dec;1832(12):2027-34. doi: 10.1016/j.bbadis.2013.07.008. Epub 2013 Jul 16. Biochim Biophys Acta. 2013. PMID: 23871839 Free article.
Lipid rafts are essential for peroxisome biogenesis in HepG2 cells.
Woudenberg J, Rembacz KP, Hoekstra M, Pellicoro A, van den Heuvel FA, Heegsma J, van Ijzendoorn SC, Holzinger A, Imanaka T, Moshage H, Faber KN. Woudenberg J, et al. Hepatology. 2010 Aug;52(2):623-33. doi: 10.1002/hep.23684. Hepatology. 2010. PMID: 20683960
Caveolin-1 is enriched in the peroxisomal membrane of rat hepatocytes.
Woudenberg J, Rembacz KP, van den Heuvel FA, Woudenberg-Vrenken TE, Buist-Homan M, Geuken M, Hoekstra M, Deelman LE, Enrich C, Henning RH, Moshage H, Faber KN. Woudenberg J, et al. Hepatology. 2010 May;51(5):1744-53. doi: 10.1002/hep.23460. Hepatology. 2010. PMID: 20146263
16 results