Wu X - Search Results

1

DSCN: Double-target selection guided by CRISPR screening and network.

Liu E, Wu X, Wang L, Huo Y, Wu H, Li L, Cheng L. Liu E, et al. Among authors: wu x, wu h. PLoS Comput Biol. 2022 Aug 19;18(8):e1009421. doi: 10.1371/journal.pcbi.1009421. eCollection 2022 Aug. PLoS Comput Biol. 2022. PMID: 35984840 Free PMC article.

2

Essentiality and Transcriptome-Enriched Pathway Scores Predict Drug-Combination Synergy.

Li J, Huo Y, Wu X, Liu E, Zeng Z, Tian Z, Fan K, Stover D, Cheng L, Li L. Li J, et al. Among authors: wu x. Biology (Basel). 2020 Sep 7;9(9):278. doi: 10.3390/biology9090278. Biology (Basel). 2020. PMID: 32906805 Free PMC article.

3

Identifying novel therapeutic targets in gastric cancer using genome-wide CRISPR-Cas9 screening.

Zeng Z, Zhang X, Jiang CQ, Zhang YG, Wu X, Li J, Tang S, Li L, Gu LJ, Xie XY, Jiang YA. Zeng Z, et al. Among authors: wu x. Oncogene. 2022 Apr;41(14):2069-2078. doi: 10.1038/s41388-022-02177-1. Epub 2022 Feb 17. Oncogene. 2022. PMID: 35177812

4

Generation of dual-gRNA library for combinatorial CRISPR screening of synthetic lethal gene pairs.

Tang S, Wu X, Liu J, Zhang Q, Wang X, Shao S, Gokbag B, Fan K, Liu X, Li F, Cheng L, Li L. Tang S, et al. Among authors: wu x. STAR Protoc. 2022 Aug 24;3(3):101556. doi: 10.1016/j.xpro.2022.101556. eCollection 2022 Sep 16. STAR Protoc. 2022. PMID: 36060092 Free PMC article.

5

Subpathway Analysis of Transcriptome Profiles Reveals New Molecular Mechanisms of Acquired Chemotherapy Resistance in Breast Cancer.

Huo Y, Shao S, Liu E, Li J, Tian Z, Wu X, Zhang S, Stover D, Wu H, Cheng L, Li L. Huo Y, et al. Among authors: wu x, wu h. Cancers (Basel). 2022 Oct 5;14(19):4878. doi: 10.3390/cancers14194878. Cancers (Basel). 2022. PMID: 36230801 Free PMC article.

6

CEDA: integrating gene expression data with CRISPR-pooled screen data identifies essential genes with higher expression.

Zhao Y, Yu L, Wu X, Li H, Coombes KR, Au KF, Cheng L, Li L. Zhao Y, et al. Among authors: wu x. Bioinformatics. 2022 Nov 30;38(23):5245-5252. doi: 10.1093/bioinformatics/btac668. Bioinformatics. 2022. PMID: 36250792 Free PMC article.

7

Synthetic lethal gene pairs: Experimental approaches and predictive models.

Tang S, Gökbağ B, Fan K, Shao S, Huo Y, Wu X, Cheng L, Li L. Tang S, et al. Among authors: wu x. Front Genet. 2022 Dec 1;13:961611. doi: 10.3389/fgene.2022.961611. eCollection 2022. Front Genet. 2022. PMID: 36531238 Free PMC article.

8

Hypoxia signaling: Challenges and opportunities for cancer therapy.

Ivan M, Fishel ML, Tudoran OM, Pollok KE, Wu X, Smith PJ. Ivan M, et al. Among authors: wu x. Semin Cancer Biol. 2022 Oct;85:185-195. doi: 10.1016/j.semcancer.2021.10.002. Epub 2021 Oct 7. Semin Cancer Biol. 2022. PMID: 34628029 Free PMC article. Review.

9

Apurinic/apyrimidinic endonuclease/redox factor-1 (APE1/Ref-1) redox function negatively regulates NRF2.

Fishel ML, Wu X, Devlin CM, Logsdon DP, Jiang Y, Luo M, He Y, Yu Z, Tong Y, Lipking KP, Maitra A, Rajeshkumar NV, Scandura G, Kelley MR, Ivan M. Fishel ML, et al. Among authors: wu x. J Biol Chem. 2015 Jan 30;290(5):3057-68. doi: 10.1074/jbc.M114.621995. Epub 2014 Dec 9. J Biol Chem. 2015. PMID: 25492865 Free PMC article.

10

Pharmacological inhibition of Carbonic Anhydrase IX and XII to enhance targeting of acute myeloid leukaemia cells under hypoxic conditions.

Chen F, Licarete E, Wu X, Petrusca D, Maguire C, Jacobsen M, Colter A, Sandusky GE, Czader M, Capitano ML, Ropa JP, Boswell HS, Carta F, Supuran CT, Parkin B, Fishel ML, Konig H. Chen F, et al. Among authors: wu x. J Cell Mol Med. 2021 Dec;25(24):11039-11052. doi: 10.1111/jcmm.17027. Epub 2021 Nov 17. J Cell Mol Med. 2021. PMID: 34791807 Free PMC article.

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