Laufer SA - Search Results

1

Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells.

Laux J, Forster M, Riexinger L, Schwamborn A, Guezguez J, Pokoj C, Kudolo M, Berger LM, Knapp S, Schollmeyer D, Guse J, Burnet M, Laufer SA. Laux J, et al. Among authors: laufer sa. ACS Pharmacol Transl Sci. 2022 Jul 14;5(8):573-602. doi: 10.1021/acsptsci.2c00054. eCollection 2022 Aug 12. ACS Pharmacol Transl Sci. 2022. PMID: 35983274 Free PMC article.

2

From five- to six-membered rings: 3,4-diarylquinolinone as lead for novel p38MAP kinase inhibitors.

Peifer C, Kinkel K, Abadleh M, Schollmeyer D, Laufer S. Peifer C, et al. J Med Chem. 2007 Mar 22;50(6):1213-21. doi: 10.1021/jm061097o. Epub 2007 Feb 27. J Med Chem. 2007. PMID: 17323937

3

Design, synthesis, and biological evaluation of novel 3-aryl-4-(1H-indole-3yl)-1,5-dihydro-2H-pyrrole-2-ones as vascular endothelial growth factor receptor (VEGF-R) inhibitors.

Peifer C, Selig R, Kinkel K, Ott D, Totzke F, Schächtele C, Heidenreich R, Röcken M, Schollmeyer D, Laufer S. Peifer C, et al. J Med Chem. 2008 Jul 10;51(13):3814-24. doi: 10.1021/jm8001185. Epub 2008 Jun 5. J Med Chem. 2008. PMID: 18529047

4

4-(4-Fluoro-phen-yl)-2-methyl-3-(1-oxy-4-pyridyl)isoxazol-5(2H)-one.

Margutti S, Schollmeyer D, Laufer S. Margutti S, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 23;64(Pt 2):o504. doi: 10.1107/S1600536807066500. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21201524 Free PMC article.

5

3-(2-Fluoro-phen-yl)-6-(phenoxy-meth-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.

Holm M, Schollmeyer D, Laufer S. Holm M, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Mar 12;64(Pt 4):o700. doi: 10.1107/S1600536808003917. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202091 Free PMC article.

6

6-Amino-1-benzyl-4-(4-chloro-phen-yl)-3-(4-pyrid-yl)-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile.

Lehmann F, Schollmeyer D, Laufer S. Lehmann F, et al. Acta Crystallogr Sect E Struct Rep Online. 2008 Mar 12;64(Pt 4):o701. doi: 10.1107/S160053680800487X. Acta Crystallogr Sect E Struct Rep Online. 2008. PMID: 21202092 Free PMC article.

7

Chiral sulfoxides as metabolites of 2-thioimidazole-based p38α mitogen-activated protein kinase inhibitors: enantioselective synthesis and biological evaluation.

Bühler S, Goettert M, Schollmeyer D, Albrecht W, Laufer SA. Bühler S, et al. Among authors: laufer sa. J Med Chem. 2011 May 12;54(9):3283-97. doi: 10.1021/jm101623p. Epub 2011 Apr 12. J Med Chem. 2011. PMID: 21449619

8

2-(4-Fluoro-phen-yl)-3-(4-pyrid-yl)pyrido[2,3-b]pyrazine.

Koch P, Schollmeyer D, Laufer S. Koch P, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 26;65(Pt 10):o2512. doi: 10.1107/S1600536809037295. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21577959 Free PMC article.

9

3-(4-Fluoro-phen-yl)-2-(4-pyrid-yl)pyrido[2,3-b]pyrazine.

Koch P, Schollmeyer D, Laufer S. Koch P, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Sep 26;65(Pt 10):o2546. doi: 10.1107/S1600536809037970. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21577988 Free PMC article.

10

N-{4-[4-(4-Fluoro-phen-yl)-1-(2-methoxy-ethyl)-2-methyl-sulfanyl-1H-imidazol-5-yl]-2-pyrid-yl}-2-methyl-3-phenyl-propionamide.

Ziegler K, Schollmeyer D, Laufer S. Ziegler K, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 21;65(Pt 12):o3128. doi: 10.1107/S1600536809048661. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21578851 Free PMC article.

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