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Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Chinthapatla R, Sotoudegan M, Anderson T, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer R, Cameron CE, Arnold JJ. Chinthapatla R, et al. Among authors: feng jy. bioRxiv [Preprint]. 2022 Aug 11:2022.08.11.503614. doi: 10.1101/2022.08.11.503614. bioRxiv. 2022. PMID: 35982684 Free PMC article. Updated. Preprint.
Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides.
Arnold JJ, Sharma SD, Feng JY, Ray AS, Smidansky ED, Kireeva ML, Cho A, Perry J, Vela JE, Park Y, Xu Y, Tian Y, Babusis D, Barauskus O, Peterson BR, Gnatt A, Kashlev M, Zhong W, Cameron CE. Arnold JJ, et al. Among authors: feng jy. PLoS Pathog. 2012;8(11):e1003030. doi: 10.1371/journal.ppat.1003030. Epub 2012 Nov 15. PLoS Pathog. 2012. PMID: 23166498 Free PMC article.
Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice.
Martinez DR, Schaefer A, Leist SR, Li D, Gully K, Yount B, Feng JY, Bunyan E, Porter DP, Cihlar T, Montgomery SA, Haynes BF, Baric RS, Nussenzweig MC, Sheahan TP. Martinez DR, et al. Among authors: feng jy. bioRxiv [Preprint]. 2021 Apr 14:2021.01.27.428478. doi: 10.1101/2021.01.27.428478. bioRxiv. 2021. PMID: 33532765 Free PMC article. Updated. Preprint.
Therapeutic efficacy of an oral nucleoside analog of remdesivir against SARS-CoV-2 pathogenesis in mice.
Schäfer A, Martinez DR, Won JJ, Moreira FR, Brown AJ, Gully KL, Kalla R, Chun K, Du Pont V, Babusis D, Tang J, Murakami E, Subramanian R, Barrett KT, Bleier BJ, Bannister R, Feng JY, Bilello JP, Cihlar T, Mackman RL, Montgomery SA, Baric RS, Sheahan TP. Schäfer A, et al. Among authors: feng jy. bioRxiv [Preprint]. 2021 Sep 17:2021.09.13.460111. doi: 10.1101/2021.09.13.460111. bioRxiv. 2021. PMID: 34545367 Free PMC article. Updated. Preprint.
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Chinthapatla R, Sotoudegan M, Srivastava P, Anderson TK, Moustafa IM, Passow KT, Kennelly SA, Moorthy R, Dulin D, Feng JY, Harki DA, Kirchdoerfer RN, Cameron CE, Arnold JJ. Chinthapatla R, et al. Among authors: feng jy. Nucleic Acids Res. 2023 Jan 11;51(1):315-336. doi: 10.1093/nar/gkac1177. Nucleic Acids Res. 2023. PMID: 36546762 Free PMC article.
Efficacy of the oral nucleoside prodrug GS-5245 (Obeldesivir) against SARS-CoV-2 and coronaviruses with pandemic potential.
Martinez DR, Moreira FR, Zweigart MR, Gully KL, De la Cruz G, Brown AJ, Adams LE, Catanzaro N, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, Montgomery SA, Perry J, Babusis D, Barrett KT, Nguyen AH, Nguyen AQ, Kalla R, Bannister R, Bilello JP, Feng JY, Cihlar T, Baric RS, Mackman RL, Schäfer A, Sheahan TP. Martinez DR, et al. Among authors: feng jy. bioRxiv [Preprint]. 2023 Jun 28:2023.06.27.546784. doi: 10.1101/2023.06.27.546784. bioRxiv. 2023. PMID: 37425890 Free PMC article. Updated. Preprint.
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.
Agostini ML, Andres EL, Sims AC, Graham RL, Sheahan TP, Lu X, Smith EC, Case JB, Feng JY, Jordan R, Ray AS, Cihlar T, Siegel D, Mackman RL, Clarke MO, Baric RS, Denison MR. Agostini ML, et al. Among authors: feng jy. mBio. 2018 Mar 6;9(2):e00221-18. doi: 10.1128/mBio.00221-18. mBio. 2018. PMID: 29511076 Free PMC article.
470 results