Mikros E - Search Results

1

Epigallocatechin gallate is a potent inhibitor of cystathionine beta-synthase: Structure-activity relationship and mechanism of action.

Zuhra K, Petrosino M, Gupta B, Panagaki T, Cecconi M, Myrianthopoulos V, Schneiter R, Mikros E, Majtan T, Szabo C. Zuhra K, et al. Among authors: mikros e. Nitric Oxide. 2022 Nov 1;128:12-24. doi: 10.1016/j.niox.2022.07.007. Epub 2022 Aug 13. Nitric Oxide. 2022. PMID: 35973674 Free article.

2

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.

Polychronopoulos P, Magiatis P, Skaltsounis AL, Myrianthopoulos V, Mikros E, Tarricone A, Musacchio A, Roe SM, Pearl L, Leost M, Greengard P, Meijer L. Polychronopoulos P, et al. Among authors: mikros e. J Med Chem. 2004 Feb 12;47(4):935-46. doi: 10.1021/jm031016d. J Med Chem. 2004. PMID: 14761195

3

An integrated computational approach to the phenomenon of potent and selective inhibition of aurora kinases B and C by a series of 7-substituted indirubins.

Myrianthopoulos V, Magiatis P, Ferandin Y, Skaltsounis AL, Meijer L, Mikros E. Myrianthopoulos V, et al. Among authors: mikros e. J Med Chem. 2007 Aug 23;50(17):4027-37. doi: 10.1021/jm070077z. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665890

4

Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.

Vougogiannopoulou K, Ferandin Y, Bettayeb K, Myrianthopoulos V, Lozach O, Fan Y, Johnson CH, Magiatis P, Skaltsounis AL, Mikros E, Meijer L. Vougogiannopoulou K, et al. Among authors: mikros e. J Med Chem. 2008 Oct 23;51(20):6421-31. doi: 10.1021/jm800648y. Epub 2008 Sep 25. J Med Chem. 2008. PMID: 18816110 Free PMC article.

5

Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family.

Kosti V, Lambrinidis G, Myrianthopoulos V, Diallinas G, Mikros E. Kosti V, et al. Among authors: mikros e. PLoS One. 2012;7(7):e41939. doi: 10.1371/journal.pone.0041939. Epub 2012 Jul 25. PLoS One. 2012. PMID: 22848666 Free PMC article.

6

Modeling, substrate docking, and mutational analysis identify residues essential for the function and specificity of a eukaryotic purine-cytosine NCS1 transporter.

Krypotou E, Kosti V, Amillis S, Myrianthopoulos V, Mikros E, Diallinas G. Krypotou E, et al. Among authors: mikros e. J Biol Chem. 2012 Oct 26;287(44):36792-803. doi: 10.1074/jbc.M112.400382. Epub 2012 Sep 11. J Biol Chem. 2012. PMID: 22969088 Free PMC article.

7

Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases.

Myrianthopoulos V, Kritsanida M, Gaboriaud-Kolar N, Magiatis P, Ferandin Y, Durieu E, Lozach O, Cappel D, Soundararajan M, Filippakopoulos P, Sherman W, Knapp S, Meijer L, Mikros E, Skaltsounis AL. Myrianthopoulos V, et al. Among authors: mikros e. ACS Med Chem Lett. 2013 Jan 10;4(1):22-26. doi: 10.1021/ml300207a. Epub 2012 Nov 1. ACS Med Chem Lett. 2013. PMID: 23336033 Free PMC article.

8

An inhibitor-driven study for enhancing the selectivity of indirubin derivatives towards leishmanial Glycogen Synthase Kinase-3 over leishmanial cdc2-related protein kinase 3.

Efstathiou A, Gaboriaud-Kolar N, Smirlis D, Myrianthopoulos V, Vougogiannopoulou K, Alexandratos A, Kritsanida M, Mikros E, Soteriadou K, Skaltsounis AL. Efstathiou A, et al. Among authors: mikros e. Parasit Vectors. 2014 May 20;7:234. doi: 10.1186/1756-3305-7-234. Parasit Vectors. 2014. PMID: 24886176 Free PMC article.

9

Discovery of the glycogen phosphorylase-modulating activity of a resveratrol glucoside by using a virtual screening protocol optimized for solvation effects.

Mavrokefalos N, Myrianthopoulos V, Chajistamatiou AS, Chrysina ED, Mikros E. Mavrokefalos N, et al. Among authors: mikros e. Planta Med. 2015 Apr;81(6):507-16. doi: 10.1055/s-0035-1545910. Epub 2015 Apr 15. Planta Med. 2015. PMID: 25875507

10

Exploring and exploiting the systemic effects of deregulated replication licensing.

Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG. Petrakis TG, et al. Among authors: mikros e. Semin Cancer Biol. 2016 Jun;37-38:3-15. doi: 10.1016/j.semcancer.2015.12.002. Epub 2015 Dec 17. Semin Cancer Biol. 2016. PMID: 26707000 Review.

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