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BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein.
Front Immunol. 2022 Jul 28;13:919815. doi: 10.3389/fimmu.2022.919815. eCollection 2022.
Front Immunol. 2022.
PMID: 35967447
Free PMC article.
Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice.
McWilliams IL, Kielczewski JL, Ireland DDC, Sykes JS, Lewkowicz AP, Konduru K, Xu BC, Chan CC, Caspi RR, Manangeeswaran M, Verthelyi D.
McWilliams IL, et al. Among authors: lewkowicz ap.
Cell Rep. 2019 Feb 12;26(7):1718-1726.e4. doi: 10.1016/j.celrep.2019.01.069.
Cell Rep. 2019.
PMID: 30759384
Free PMC article.
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CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF.
Manangeeswaran M, Lewkowicz AP, Israely T, Ireland DDC, Verthelyi D.
Manangeeswaran M, et al. Among authors: lewkowicz ap.
Front Immunol. 2020 Feb 18;11:237. doi: 10.3389/fimmu.2020.00237. eCollection 2020.
Front Immunol. 2020.
PMID: 32133008
Free PMC article.
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Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice.
Ireland DDC, Manangeeswaran M, Lewkowicz AP, Engel K, Clark SM, Laniyan A, Sykes J, Lee HN, McWilliams IL, Kelley-Baker L, Tonelli LH, Verthelyi D.
Ireland DDC, et al. Among authors: lewkowicz ap.
PLoS Pathog. 2020 Dec 10;16(12):e1008689. doi: 10.1371/journal.ppat.1008689. eCollection 2020 Dec.
PLoS Pathog. 2020.
PMID: 33301527
Free PMC article.
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Characterization of the therapeutic effect of antibodies targeting the Ebola glycoprotein using a novel BSL2-compliant rVSVΔG-EBOV-GP infection model.
Lee HN, McWilliams IL, Lewkowicz AP, Engel K, Ireland DDC, Kelley-Baker L, Thacker S, Piccardo P, Manangeeswaran M, Verthelyi D.
Lee HN, et al. Among authors: lewkowicz ap.
Emerg Microbes Infect. 2021 Dec;10(1):2076-2089. doi: 10.1080/22221751.2021.1997075.
Emerg Microbes Infect. 2021.
PMID: 34674613
Free PMC article.
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NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.
Lee HN, Manangeeswaran M, Lewkowicz AP, Engel K, Chowdhury M, Garige M, Eckhaus MA, Sourbier C, Ireland DD, Verthelyi D.
Lee HN, et al. Among authors: lewkowicz ap.
JCI Insight. 2022 Feb 8;7(3):e151420. doi: 10.1172/jci.insight.151420.
JCI Insight. 2022.
PMID: 35132958
Free PMC article.
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Neonatal Zika virus infection causes transient perineuronal net degradation.
Engel K, Lee HN, Tewari BP, Lewkowicz AP, Ireland DDC, Manangeeswaran M, Verthelyi D.
Engel K, et al. Among authors: lewkowicz ap.
Front Cell Neurosci. 2023 Jul 11;17:1187425. doi: 10.3389/fncel.2023.1187425. eCollection 2023.
Front Cell Neurosci. 2023.
PMID: 37496706
Free PMC article.
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Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeutics.
Lee HN, Xu B, Lewkowicz AP, Engel K, Kelley-Baker L, McWilliams IL, Ireland DDC, Kielczewski JL, Li J, Fariss RN, Campos MM, Baum A, Kyratsous C, Pascal K, Chan CC, Caspi RR, Manangeeswaran M, Verthelyi D.
Lee HN, et al. Among authors: lewkowicz ap.
EBioMedicine. 2024 May 31;104:105170. doi: 10.1016/j.ebiom.2024.105170. Online ahead of print.
EBioMedicine. 2024.
PMID: 38823088
Free article.
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