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BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein.
Front Immunol. 2022 Jul 28;13:919815. doi: 10.3389/fimmu.2022.919815. eCollection 2022.
Front Immunol. 2022.
PMID: 35967447
Free PMC article.
Characterization of the therapeutic effect of antibodies targeting the Ebola glycoprotein using a novel BSL2-compliant rVSVΔG-EBOV-GP infection model.
Lee HN, McWilliams IL, Lewkowicz AP, Engel K, Ireland DDC, Kelley-Baker L, Thacker S, Piccardo P, Manangeeswaran M, Verthelyi D.
Lee HN, et al. Among authors: kelley baker l.
Emerg Microbes Infect. 2021 Dec;10(1):2076-2089. doi: 10.1080/22221751.2021.1997075.
Emerg Microbes Infect. 2021.
PMID: 34674613
Free PMC article.
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Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients.
Thacker SG, Her C, Kelley-Baker L, Ireland DDC, Manangeeswaran M, Pang ES, Verthelyi D.
Thacker SG, et al. Among authors: kelley baker l.
Front Immunol. 2022 Sep 6;13:970499. doi: 10.3389/fimmu.2022.970499. eCollection 2022.
Front Immunol. 2022.
PMID: 36148237
Free PMC article.
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Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice.
Ireland DDC, Manangeeswaran M, Lewkowicz AP, Engel K, Clark SM, Laniyan A, Sykes J, Lee HN, McWilliams IL, Kelley-Baker L, Tonelli LH, Verthelyi D.
Ireland DDC, et al. Among authors: kelley baker l.
PLoS Pathog. 2020 Dec 10;16(12):e1008689. doi: 10.1371/journal.ppat.1008689. eCollection 2020 Dec.
PLoS Pathog. 2020.
PMID: 33301527
Free PMC article.
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Detection of innate immune response modulating impurities in therapeutic proteins.
Haile LA, Puig M, Kelley-Baker L, Verthelyi D.
Haile LA, et al. Among authors: kelley baker l.
PLoS One. 2015 Apr 22;10(4):e0125078. doi: 10.1371/journal.pone.0125078. eCollection 2015.
PLoS One. 2015.
PMID: 25901912
Free PMC article.
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Cell based assay identifies TLR2 and TLR4 stimulating impurities in Interferon beta.
Haile LA, Polumuri SK, Rao R, Kelley-Baker L, Kryndushkin D, Rajaiah R, Israely T, Rao VA, Verthelyi D.
Haile LA, et al. Among authors: kelley baker l.
Sci Rep. 2017 Sep 5;7(1):10490. doi: 10.1038/s41598-017-09981-w.
Sci Rep. 2017.
PMID: 28874687
Free PMC article.
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Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeutics.
Lee HN, Xu B, Lewkowicz AP, Engel K, Kelley-Baker L, McWilliams IL, Ireland DDC, Kielczewski JL, Li J, Fariss RN, Campos MM, Baum A, Kyratsous C, Pascal K, Chan CC, Caspi RR, Manangeeswaran M, Verthelyi D.
Lee HN, et al. Among authors: kelley baker l.
EBioMedicine. 2024 May 31;104:105170. doi: 10.1016/j.ebiom.2024.105170. Online ahead of print.
EBioMedicine. 2024.
PMID: 38823088
Free article.
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