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Monoclonal antibodies effectively potentiate complement activation and phagocytosis of Staphylococcus epidermidis in neonatal human plasma.
de Vor L, Beudeker CR, Flier A, Scheepmaker LM, Aerts PC, Vijlbrief DC, Bekker MN, Beurskens FJ, van Kessel KPM, de Haas CJC, Rooijakkers SHM, van der Flier M. de Vor L, et al. Among authors: beurskens fj. Front Immunol. 2022 Jul 29;13:933251. doi: 10.3389/fimmu.2022.933251. eCollection 2022. Front Immunol. 2022. PMID: 35967335 Free PMC article.
Complement activation by (auto-) antibodies.
Daha NA, Banda NK, Roos A, Beurskens FJ, Bakker JM, Daha MR, Trouw LA. Daha NA, et al. Among authors: beurskens fj. Mol Immunol. 2011 Aug;48(14):1656-65. doi: 10.1016/j.molimm.2011.04.024. Epub 2011 Jul 14. Mol Immunol. 2011. PMID: 21757235 Review.
Complement in antibody-based tumor therapy.
Derer S, Beurskens FJ, Rosner T, Peipp M, Valerius T. Derer S, et al. Among authors: beurskens fj. Crit Rev Immunol. 2014;34(3):199-214. doi: 10.1615/critrevimmunol.2014009761. Crit Rev Immunol. 2014. PMID: 24941073 Review.
Real-time analysis of the detailed sequence of cellular events in mAb-mediated complement-dependent cytotoxicity of B-cell lines and of chronic lymphocytic leukemia B-cells.
Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, de Jong RN, Beurskens FJ, Schuurman J, Parren PW, Taylor RP. Lindorfer MA, et al. Among authors: beurskens fj. Mol Immunol. 2016 Feb;70:13-23. doi: 10.1016/j.molimm.2015.12.007. Epub 2015 Dec 12. Mol Immunol. 2016. PMID: 26690706
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells.
Tammen A, Derer S, Schwanbeck R, Rösner T, Kretschmer A, Beurskens FJ, Schuurman J, Parren PW, Valerius T. Tammen A, et al. Among authors: beurskens fj. J Immunol. 2017 Feb 15;198(4):1585-1594. doi: 10.4049/jimmunol.1601268. Epub 2017 Jan 6. J Immunol. 2017. PMID: 28062698
57 results