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The ESX-4 substrates, EsxU and EsxT, modulate Mycobacterium abscessus fitness.
Lagune M, Le Moigne V, Johansen MD, Vásquez Sotomayor F, Daher W, Petit C, Cosentino G, Paulowski L, Gutsmann T, Wilmanns M, Maurer FP, Herrmann JL, Girard-Misguich F, Kremer L. Lagune M, et al. Among authors: girard misguich f. PLoS Pathog. 2022 Aug 12;18(8):e1010771. doi: 10.1371/journal.ppat.1010771. eCollection 2022 Aug. PLoS Pathog. 2022. PMID: 35960766 Free PMC article.
Mycobacterium abscessus phospholipase C expression is induced during coculture within amoebae and enhances M. abscessus virulence in mice.
Bakala N'Goma JC, Le Moigne V, Soismier N, Laencina L, Le Chevalier F, Roux AL, Poncin I, Serveau-Avesque C, Rottman M, Gaillard JL, Etienne G, Brosch R, Herrmann JL, Canaan S, Girard-Misguich F. Bakala N'Goma JC, et al. Infect Immun. 2015 Feb;83(2):780-91. doi: 10.1128/IAI.02032-14. Epub 2014 Dec 8. Infect Immun. 2015. PMID: 25486995 Free PMC article.
Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.
Laencina L, Dubois V, Le Moigne V, Viljoen A, Majlessi L, Pritchard J, Bernut A, Piel L, Roux AL, Gaillard JL, Lombard B, Loew D, Rubin EJ, Brosch R, Kremer L, Herrmann JL, Girard-Misguich F. Laencina L, et al. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E1002-E1011. doi: 10.1073/pnas.1713195115. Epub 2018 Jan 17. Proc Natl Acad Sci U S A. 2018. PMID: 29343644 Free PMC article.
MmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family.
Dubois V, Viljoen A, Laencina L, Le Moigne V, Bernut A, Dubar F, Blaise M, Gaillard JL, Guérardel Y, Kremer L, Herrmann JL, Girard-Misguich F. Dubois V, et al. Among authors: girard misguich f. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10147-E10156. doi: 10.1073/pnas.1812984115. Epub 2018 Oct 9. Proc Natl Acad Sci U S A. 2018. PMID: 30301802 Free PMC article.
[The most ancestral mycobacterial ESX-4 secretion system is essential for intracellular growth of Mycobacterium abscessus within environmental and human phagocytes].
Girard-Misguich F, Laencina L, Dubois V, Le Moigne V, Kremer L, Maljessi L, Brosch R, Herrmann JL. Girard-Misguich F, et al. Med Sci (Paris). 2018 Oct;34(10):795-797. doi: 10.1051/medsci/2018196. Epub 2018 Nov 19. Med Sci (Paris). 2018. PMID: 30451667 Free article. French. No abstract available.
Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages.
Dubois V, Pawlik A, Bories A, Le Moigne V, Sismeiro O, Legendre R, Varet H, Rodríguez-Ordóñez MDP, Gaillard JL, Coppée JY, Brosch R, Herrmann JL, Girard-Misguich F. Dubois V, et al. Among authors: girard misguich f. PLoS Pathog. 2019 Nov 8;15(11):e1008069. doi: 10.1371/journal.ppat.1008069. eCollection 2019 Nov. PLoS Pathog. 2019. PMID: 31703112 Free PMC article.
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