Jensen AA - Search Results

1

Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype.

Chałupnik P, Vialko A, Pickering DS, Hinkkanen M, Donbosco S, Møller TC, Jensen AA, Nielsen B, Bay Y, Kristensen AS, Johansen TN, Łątka K, Bajda M, Szymańska E. Chałupnik P, et al. Among authors: jensen aa. Int J Mol Sci. 2022 Aug 8;23(15):8797. doi: 10.3390/ijms23158797. Int J Mol Sci. 2022. PMID: 35955932 Free PMC article.

2

The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors.

Jensen AA, Mosbacher J, Elg S, Lingenhoehl K, Lohmann T, Johansen TN, Abrahamsen B, Mattsson JP, Lehmann A, Bettler B, Bräuner-Osborne H. Jensen AA, et al. Mol Pharmacol. 2002 Jun;61(6):1377-84. doi: 10.1124/mol.61.6.1377. Mol Pharmacol. 2002. PMID: 12021399

3

Azetidinic amino acids: stereocontrolled synthesis and pharmacological characterization as ligands for glutamate receptors and transporters.

Bräuner-Osborne H, Bunch L, Chopin N, Couty F, Evano G, Jensen AA, Kusk M, Nielsen B, Rabasso N. Bräuner-Osborne H, et al. Among authors: jensen aa. Org Biomol Chem. 2005 Nov 7;3(21):3926-36. doi: 10.1039/b509514j. Epub 2005 Sep 29. Org Biomol Chem. 2005. PMID: 16240010

4

Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3.

Bunch L, Nielsen B, Jensen AA, Bräuner-Osborne H. Bunch L, et al. Among authors: jensen aa. J Med Chem. 2006 Jan 12;49(1):172-8. doi: 10.1021/jm0508336. J Med Chem. 2006. PMID: 16392801

5

5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists.

Madsen C, Jensen AA, Liljefors T, Kristiansen U, Nielsen B, Hansen CP, Larsen M, Ebert B, Bang-Andersen B, Krogsgaard-Larsen P, Frølund B. Madsen C, et al. Among authors: jensen aa. J Med Chem. 2007 Aug 23;50(17):4147-61. doi: 10.1021/jm070447j. Epub 2007 Jul 26. J Med Chem. 2007. PMID: 17655213

6

Functional characterization of Tet-AMPA [tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic acid] analogues at ionotropic glutamate receptors GluR1-GluR4. The molecular basis for the functional selectivity profile of 2-Bn-Tet-AMPA.

Jensen AA, Christesen T, Bølcho U, Greenwood JR, Postorino G, Vogensen SB, Johansen TN, Egebjerg J, Bräuner-Osborne H, Clausen RP. Jensen AA, et al. J Med Chem. 2007 Aug 23;50(17):4177-85. doi: 10.1021/jm070532r. Epub 2007 Aug 2. J Med Chem. 2007. PMID: 17672447

7

Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2.

Sagot E, Jensen AA, Pickering DS, Pu X, Umberti M, Stensbøl TB, Nielsen B, Assaf Z, Aboab B, Bolte J, Gefflaut T, Bunch L. Sagot E, et al. Among authors: jensen aa. J Med Chem. 2008 Jul 24;51(14):4085-92. doi: 10.1021/jm800091e. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578477 Free article.

8

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.

Clausen RP, Naur P, Kristensen AS, Greenwood JR, Strange M, Bräuner-Osborne H, Jensen AA, Nielsen AS, Geneser U, Ringgaard LM, Nielsen B, Pickering DS, Brehm L, Gajhede M, Krogsgaard-Larsen P, Kastrup JS. Clausen RP, et al. Among authors: jensen aa. J Med Chem. 2009 Aug 13;52(15):4911-22. doi: 10.1021/jm900565c. J Med Chem. 2009. PMID: 19588945

9

4,4-Dimethyl- and diastereomeric 4-hydroxy-4-methyl- (2S)-glutamate analogues display distinct pharmacological profiles at ionotropic glutamate receptors and excitatory amino acid transporters.

Bunch L, Pickering DS, Gefflaut T, Vinatier V, Helaine V, Amir A, Nielsen B, Jensen AA. Bunch L, et al. Among authors: jensen aa. ChemMedChem. 2009 Nov;4(11):1925-9. doi: 10.1002/cmdc.200900258. ChemMedChem. 2009. PMID: 19731281

10

Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as gamma-aminobutyric acid(A) receptor ligands: synthesis, pharmacology, and structure-activity relationships.

Møller HA, Sander T, Kristensen JL, Nielsen B, Krall J, Bergmann ML, Christiansen B, Balle T, Jensen AA, Frølund B. Møller HA, et al. Among authors: jensen aa. J Med Chem. 2010 Apr 22;53(8):3417-21. doi: 10.1021/jm100106r. J Med Chem. 2010. PMID: 20355712

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