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mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I, Pollard S, Lovell-Badge R, Sampron N, Garcia I, Matheu A. Garros-Regulez L, et al. Among authors: matheu a. Expert Opin Ther Targets. 2016;20(4):393-405. doi: 10.1517/14728222.2016.1151002. Expert Opin Ther Targets. 2016. PMID: 26878385 Free PMC article.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.
Arrizabalaga O, Moreno-Cugnon L, Auzmendi-Iriarte J, Aldaz P, Ibanez de Caceres I, Garros-Regulez L, Moncho-Amor V, Torres-Bayona S, Pernía O, Pintado-Berninches L, Carrasco-Ramirez P, Cortes-Sempere M, Rosas R, Sanchez-Gomez P, Ruiz I, Caren H, Pollard S, Garcia I, Sacido AA, Lovell-Badge R, Belda-Iniesta C, Sampron N, Perona R, Matheu A. Arrizabalaga O, et al. Among authors: matheu a. Oncogenesis. 2017 Dec 14;6(12):401. doi: 10.1038/s41389-017-0003-9. Oncogenesis. 2017. PMID: 29284798 Free PMC article.
Targeting mTOR as a Therapeutic Approach in Medulloblastoma.
Aldaregia J, Odriozola A, Matheu A, Garcia I. Aldaregia J, et al. Among authors: matheu a. Int J Mol Sci. 2018 Jun 22;19(7):1838. doi: 10.3390/ijms19071838. Int J Mol Sci. 2018. PMID: 29932116 Free PMC article. Review.
Primary cilium and glioblastoma.
Álvarez-Satta M, Matheu A. Álvarez-Satta M, et al. Among authors: matheu a. Ther Adv Med Oncol. 2018 Oct 3;10:1758835918801169. doi: 10.1177/1758835918801169. eCollection 2018. Ther Adv Med Oncol. 2018. PMID: 30302130 Free PMC article. Review.
Therapeutic relevance of SOX9 stem cell factor in gastric cancer.
Carrasco-Garcia E, Álvarez-Satta M, García-Puga M, Ribeiro ML, Arevalo S, Arauzo-Bravo M, Matheu A. Carrasco-Garcia E, et al. Among authors: matheu a. Expert Opin Ther Targets. 2019 Feb;23(2):143-152. doi: 10.1080/14728222.2019.1559826. Epub 2018 Dec 20. Expert Opin Ther Targets. 2019. PMID: 30572738 Review.
Neuronal p38α mediates age-associated neural stem cell exhaustion and cognitive decline.
Moreno-Cugnon L, Revuelta M, Arrizabalaga O, Colie S, Moreno-Valladares M, Jimenez-Blasco D, Gil-Bea F, Llarena I, Bolaños JP, Nebreda AR, Matheu A. Moreno-Cugnon L, et al. Among authors: matheu a. Aging Cell. 2019 Dec;18(6):e13044. doi: 10.1111/acel.13044. Epub 2019 Sep 27. Aging Cell. 2019. PMID: 31560167 Free PMC article.
SOX9 promotes tumor progression through the axis BMI1-p21CIP.
Aldaz P, Otaegi-Ugartemendia M, Saenz-Antoñanzas A, Garcia-Puga M, Moreno-Valladares M, Flores JM, Gerovska D, Arauzo-Bravo MJ, Samprón N, Matheu A, Carrasco-Garcia E. Aldaz P, et al. Among authors: matheu a. Sci Rep. 2020 Jan 15;10(1):357. doi: 10.1038/s41598-019-57047-w. Sci Rep. 2020. PMID: 31941916 Free PMC article.
125 results