Pietrobono S - Search Results

1

p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells.

Pietrobono S, De Paolo R, Mangiameli D, Marranci A, Battisti I, Franchin C, Arrigoni G, Melisi D, Poliseno L, Stecca B. Pietrobono S, et al. J Biol Chem. 2022 Sep;298(9):102353. doi: 10.1016/j.jbc.2022.102353. Epub 2022 Aug 7. J Biol Chem. 2022. PMID: 35944584 Free PMC article.

2

SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells.

Santini R, Pietrobono S, Pandolfi S, Montagnani V, D'Amico M, Penachioni JY, Vinci MC, Borgognoni L, Stecca B. Santini R, et al. Among authors: pietrobono s. Oncogene. 2014 Sep 18;33(38):4697-708. doi: 10.1038/onc.2014.71. Epub 2014 Mar 31. Oncogene. 2014. PMID: 24681955 Free PMC article.

3

Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival.

Pietrobono S, Morandi A, Gagliardi S, Gerlini G, Borgognoni L, Chiarugi P, Arbiser JL, Stecca B. Pietrobono S, et al. J Invest Dermatol. 2016 Oct;136(10):2059-2069. doi: 10.1016/j.jid.2016.06.610. Epub 2016 Jun 29. J Invest Dermatol. 2016. PMID: 27373978 Free article.

4

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.

Pietrobono S, Santini R, Gagliardi S, Dapporto F, Colecchia D, Chiariello M, Leone C, Valoti M, Manetti F, Petricci E, Taddei M, Stecca B. Pietrobono S, et al. Cell Death Dis. 2018 Feb 2;9(2):142. doi: 10.1038/s41419-017-0142-0. Cell Death Dis. 2018. PMID: 29396391 Free PMC article.

5

SOX2 as a novel contributor of oxidative metabolism in melanoma cells.

Andreucci E, Pietrobono S, Peppicelli S, Ruzzolini J, Bianchini F, Biagioni A, Stecca B, Calorini L. Andreucci E, et al. Among authors: pietrobono s. Cell Commun Signal. 2018 Nov 22;16(1):87. doi: 10.1186/s12964-018-0297-z. Cell Commun Signal. 2018. PMID: 30466459 Free PMC article.

6

Targeting the Oncoprotein Smoothened by Small Molecules: Focus on Novel Acylguanidine Derivatives as Potent Smoothened Inhibitors.

Pietrobono S, Stecca B. Pietrobono S, et al. Cells. 2018 Dec 14;7(12):272. doi: 10.3390/cells7120272. Cells. 2018. PMID: 30558232 Free PMC article. Review.

7

Non-canonical Hedgehog Signaling Pathway in Cancer: Activation of GLI Transcription Factors Beyond Smoothened.

Pietrobono S, Gagliardi S, Stecca B. Pietrobono S, et al. Front Genet. 2019 Jun 12;10:556. doi: 10.3389/fgene.2019.00556. eCollection 2019. Front Genet. 2019. PMID: 31244888 Free PMC article. Review.

8

ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL.

Pietrobono S, Anichini G, Sala C, Manetti F, Almada LL, Pepe S, Carr RM, Paradise BD, Sarkaria JN, Davila JI, Tofani L, Battisti I, Arrigoni G, Ying L, Zhang C, Li H, Meves A, Fernandez-Zapico ME, Stecca B. Pietrobono S, et al. Nat Commun. 2020 Nov 17;11(1):5865. doi: 10.1038/s41467-020-19575-2. Nat Commun. 2020. PMID: 33203881 Free PMC article.

9

Aberrant Sialylation in Cancer: Biomarker and Potential Target for Therapeutic Intervention?

Pietrobono S, Stecca B. Pietrobono S, et al. Cancers (Basel). 2021 Apr 22;13(9):2014. doi: 10.3390/cancers13092014. Cancers (Basel). 2021. PMID: 33921986 Free PMC article. Review.

10

Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma.

Pietrobono S, Gaudio E, Gagliardi S, Zitani M, Carrassa L, Migliorini F, Petricci E, Manetti F, Makukhin N, Bond AG, Paradise BD, Ciulli A, Fernandez-Zapico ME, Bertoni F, Stecca B. Pietrobono S, et al. Oncogene. 2021 Jun;40(22):3799-3814. doi: 10.1038/s41388-021-01783-9. Epub 2021 May 6. Oncogene. 2021. PMID: 33958721 Free PMC article.

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