Haigis KM - Search Results

1

Functional and biological heterogeneity of KRAS^Q61 mutations.

Huynh MV, Hobbs GA, Schaefer A, Pierobon M, Carey LM, Diehl JN, DeLiberty JM, Thurman RD, Cooke AR, Goodwin CM, Cook JH, Lin L, Waters AM, Rashid NU, Petricoin EF 3rd, Campbell SL, Haigis KM, Simeone DM, Lyssiotis CA, Cox AD, Der CJ. Huynh MV, et al. Among authors: haigis km. Sci Signal. 2022 Aug 9;15(746):eabn2694. doi: 10.1126/scisignal.abn2694. Epub 2022 Aug 9. Sci Signal. 2022. PMID: 35944066 Free PMC article.

2

Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.

Wang Y, Velho S, Vakiani E, Peng S, Bass AJ, Chu GC, Gierut J, Bugni JM, Der CJ, Philips M, Solit DB, Haigis KM. Wang Y, et al. Among authors: haigis km. Cancer Discov. 2013 Mar;3(3):294-307. doi: 10.1158/2159-8290.CD-12-0198. Epub 2012 Dec 28. Cancer Discov. 2013. PMID: 23274911 Free PMC article.

3

K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif.

Tsai FD, Lopes MS, Zhou M, Court H, Ponce O, Fiordalisi JJ, Gierut JJ, Cox AD, Haigis KM, Philips MR. Tsai FD, et al. Among authors: haigis km. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):779-84. doi: 10.1073/pnas.1412811112. Epub 2015 Jan 5. Proc Natl Acad Sci U S A. 2015. PMID: 25561545 Free PMC article.

4

Tissue-Specific Oncogenic Activity of KRAS^A146T.

Poulin EJ, Bera AK, Lu J, Lin YJ, Strasser SD, Paulo JA, Huang TQ, Morales C, Yan W, Cook J, Nowak JA, Brubaker DK, Joughin BA, Johnson CW, DeStefanis RA, Ghazi PC, Gondi S, Wales TE, Iacob RE, Bogdanova L, Gierut JJ, Li Y, Engen JR, Perez-Mancera PA, Braun BS, Gygi SP, Lauffenburger DA, Westover KD, Haigis KM. Poulin EJ, et al. Among authors: haigis km. Cancer Discov. 2019 Jun;9(6):738-755. doi: 10.1158/2159-8290.CD-18-1220. Epub 2019 Apr 5. Cancer Discov. 2019. PMID: 30952657 Free PMC article.

5

The origins and genetic interactions of KRAS mutations are allele- and tissue-specific.

Cook JH, Melloni GEM, Gulhan DC, Park PJ, Haigis KM. Cook JH, et al. Among authors: haigis km. Nat Commun. 2021 Mar 22;12(1):1808. doi: 10.1038/s41467-021-22125-z. Nat Commun. 2021. PMID: 33753749 Free PMC article.

6

Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention.

Johnson C, Burkhart DL, Haigis KM. Johnson C, et al. Among authors: haigis km. Cancer Discov. 2022 Apr 1;12(4):913-923. doi: 10.1158/2159-8290.CD-22-0035. Cancer Discov. 2022. PMID: 35373279 Free PMC article.

7

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.

Haigis KM, Kendall KR, Wang Y, Cheung A, Haigis MC, Glickman JN, Niwa-Kawakita M, Sweet-Cordero A, Sebolt-Leopold J, Shannon KM, Settleman J, Giovannini M, Jacks T. Haigis KM, et al. Among authors: haigis mc. Nat Genet. 2008 May;40(5):600-8. doi: 10.1038/ng.115. Epub 2008 Mar 30. Nat Genet. 2008. PMID: 18372904 Free PMC article.

8

NRAS mutations are rare in colorectal cancer.

Irahara N, Baba Y, Nosho K, Shima K, Yan L, Dias-Santagata D, Iafrate AJ, Fuchs CS, Haigis KM, Ogino S. Irahara N, et al. Among authors: haigis km. Diagn Mol Pathol. 2010 Sep;19(3):157-63. doi: 10.1097/PDM.0b013e3181c93fd1. Diagn Mol Pathol. 2010. PMID: 20736745 Free PMC article.

9

Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.

Tanaka N, Huttenhower C, Nosho K, Baba Y, Shima K, Quackenbush J, Haigis KM, Giovannucci E, Fuchs CS, Ogino S. Tanaka N, et al. Among authors: haigis km. Am J Pathol. 2010 Dec;177(6):2731-40. doi: 10.2353/ajpath.2010.100361. Epub 2010 Oct 29. Am J Pathol. 2010. PMID: 21037082 Free PMC article.

10

Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.

Imamura Y, Morikawa T, Liao X, Lochhead P, Kuchiba A, Yamauchi M, Qian ZR, Nishihara R, Meyerhardt JA, Haigis KM, Fuchs CS, Ogino S. Imamura Y, et al. Among authors: haigis km. Clin Cancer Res. 2012 Sep 1;18(17):4753-63. doi: 10.1158/1078-0432.CCR-11-3210. Epub 2012 Jul 2. Clin Cancer Res. 2012. PMID: 22753589 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

98 results

Search Page