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Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, Ranjan A, Devost D, Namkung Y, Stepniewski TM, Pandey S, Baruah M, Panigrahi B, Sarma P, Yadav MK, Maharana J, Banerjee R, Kawakami K, Inoue A, Selent J, Laporte SA, Hébert TE, Shukla AK. Baidya M, et al. Among authors: chaturvedi m. Nat Commun. 2022 Aug 8;13(1):4634. doi: 10.1038/s41467-022-32386-x. Nat Commun. 2022. PMID: 35941121 Free PMC article.
Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms.
Ghosh E, Dwivedi H, Baidya M, Srivastava A, Kumari P, Stepniewski T, Kim HR, Lee MH, van Gastel J, Chaturvedi M, Roy D, Pandey S, Maharana J, Guixà-González R, Luttrell LM, Chung KY, Dutta S, Selent J, Shukla AK. Ghosh E, et al. Among authors: chaturvedi m. Cell Rep. 2019 Sep 24;28(13):3287-3299.e6. doi: 10.1016/j.celrep.2019.08.053. Cell Rep. 2019. PMID: 31553900 Free PMC article.
Calcium as a biased cofactor.
Chaturvedi M, Shukla AK. Chaturvedi M, et al. Science. 2020 Apr 24;368(6489):369-370. doi: 10.1126/science.abb4393. Science. 2020. PMID: 32327587 Free PMC article. No abstract available.
Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein-coupled receptors.
Baidya M, Kumari P, Dwivedi-Agnihotri H, Pandey S, Sokrat B, Sposini S, Chaturvedi M, Srivastava A, Roy D, Hanyaloglu AC, Bouvier M, Shukla AK. Baidya M, et al. Among authors: chaturvedi m. J Biol Chem. 2020 Jul 24;295(30):10153-10167. doi: 10.1074/jbc.RA120.013470. Epub 2020 May 21. J Biol Chem. 2020. PMID: 32439801 Free PMC article.
Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor.
Lee Y, Warne T, Nehmé R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, García-Nafría J, Leslie AGW, Shukla AK, Tate CG. Lee Y, et al. Among authors: chaturvedi m. Nature. 2020 Jul;583(7818):862-866. doi: 10.1038/s41586-020-2419-1. Epub 2020 Jun 17. Nature. 2020. PMID: 32555462 Free PMC article.
Crystal Structure of β-Arrestin 2 in Complex with CXCR7 Phosphopeptide.
Min K, Yoon HJ, Park JY, Baidya M, Dwivedi-Agnihotri H, Maharana J, Chaturvedi M, Chung KY, Shukla AK, Lee HH. Min K, et al. Among authors: chaturvedi m. Structure. 2020 Sep 1;28(9):1014-1023.e4. doi: 10.1016/j.str.2020.06.002. Epub 2020 Jun 23. Structure. 2020. PMID: 32579945 Free PMC article.
233 results