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Transcription Factor GATA4 Regulates Cell Type-Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitors.
Zhu L, Choudhary K, Gonzalez-Teran B, Ang YS, Thomas R, Stone NR, Liu L, Zhou P, Zhu C, Ruan H, Huang Y, Jin S, Pelonero A, Koback F, Padmanabhan A, Sadagopan N, Hsu A, Costa MW, Gifford CA, van Bemmel JG, Hüttenhain R, Vedantham V, Conklin BR, Black BL, Bruneau BG, Steinmetz L, Krogan NJ, Pollard KS, Srivastava D. Zhu L, et al. Among authors: gifford ca. Circulation. 2022 Sep 6;146(10):770-787. doi: 10.1161/CIRCULATIONAHA.121.057620. Epub 2022 Aug 8. Circulation. 2022. PMID: 35938400 Free PMC article.
Differentiation of V2a interneurons from human pluripotent stem cells.
Butts JC, McCreedy DA, Martinez-Vargas JA, Mendoza-Camacho FN, Hookway TA, Gifford CA, Taneja P, Noble-Haeusslein L, McDevitt TC. Butts JC, et al. Among authors: gifford ca. Proc Natl Acad Sci U S A. 2017 May 9;114(19):4969-4974. doi: 10.1073/pnas.1608254114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28438991 Free PMC article.
Oligogenic inheritance of a human heart disease involving a genetic modifier.
Gifford CA, Ranade SS, Samarakoon R, Salunga HT, de Soysa TY, Huang Y, Zhou P, Elfenbein A, Wyman SK, Bui YK, Cordes Metzler KR, Ursell P, Ivey KN, Srivastava D. Gifford CA, et al. Science. 2019 May 31;364(6443):865-870. doi: 10.1126/science.aat5056. Epub 2019 May 30. Science. 2019. PMID: 31147515 Free PMC article.
Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming.
Stone NR, Gifford CA, Thomas R, Pratt KJB, Samse-Knapp K, Mohamed TMA, Radzinsky EM, Schricker A, Ye L, Yu P, van Bemmel JG, Ivey KN, Pollard KS, Srivastava D. Stone NR, et al. Among authors: gifford ca. Cell Stem Cell. 2019 Jul 3;25(1):87-102.e9. doi: 10.1016/j.stem.2019.06.012. Cell Stem Cell. 2019. PMID: 31271750 Free PMC article.
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Among authors: gifford ca. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
Transcription factor protein interactomes reveal genetic determinants in heart disease.
Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, Morton SU, McGregor M, Gifford CA, Seidman JG, Seidman CE, Gelb BD, Colombo G, Conklin BR, Black BL, Bruneau BG, Krogan NJ, Pollard KS, Srivastava D. Gonzalez-Teran B, et al. Among authors: gifford ca. Cell. 2022 Mar 3;185(5):794-814.e30. doi: 10.1016/j.cell.2022.01.021. Epub 2022 Feb 18. Cell. 2022. PMID: 35182466 Free PMC article.
The multi-lineage transcription factor ISL1 controls cardiomyocyte cell fate through interaction with NKX2.5.
Maven BEJ, Gifford CA, Weilert M, Gonzalez-Teran B, Hüttenhain R, Pelonero A, Ivey KN, Samse-Knapp K, Kwong W, Gordon D, McGregor M, Nishino T, Okorie E, Rossman S, Costa MW, Krogan NJ, Zeitlinger J, Srivastava D. Maven BEJ, et al. Among authors: gifford ca. Stem Cell Reports. 2023 Nov 14;18(11):2138-2153. doi: 10.1016/j.stemcr.2023.09.014. Epub 2023 Oct 19. Stem Cell Reports. 2023. PMID: 37863045 Free PMC article.
57 results