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Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice.
Bernier M, Enamorado IN, Gómez-Cabrera MC, Calvo-Rubio M, González-Reyes JA, Price NL, Cortés-Rodríguez AB, Rodríguez-Aguilera JC, Rodríguez-López S, Mitchell SJ, Murt KN, Kalafut K, Williams KM, Ward CW, Stains JP, Brea-Calvo G, Villalba JM, Cortassa S, Aon MA, de Cabo R. Bernier M, et al. Among authors: mitchell sj. NPJ Aging. 2022 Jun 27;8(1):8. doi: 10.1038/s41514-022-00089-8. NPJ Aging. 2022. PMID: 35927269 Free PMC article.
Metformin improves healthspan and lifespan in mice.
Martin-Montalvo A, Mercken EM, Mitchell SJ, Palacios HH, Mote PL, Scheibye-Knudsen M, Gomes AP, Ward TM, Minor RK, Blouin MJ, Schwab M, Pollak M, Zhang Y, Yu Y, Becker KG, Bohr VA, Ingram DK, Sinclair DA, Wolf NS, Spindler SR, Bernier M, de Cabo R. Martin-Montalvo A, et al. Among authors: mitchell sj. Nat Commun. 2013;4:2192. doi: 10.1038/ncomms3192. Nat Commun. 2013. PMID: 23900241 Free PMC article.
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet.
Mitchell SJ, Martin-Montalvo A, Mercken EM, Palacios HH, Ward TM, Abulwerdi G, Minor RK, Vlasuk GP, Ellis JL, Sinclair DA, Dawson J, Allison DB, Zhang Y, Becker KG, Bernier M, de Cabo R. Mitchell SJ, et al. Cell Rep. 2014 Mar 13;6(5):836-43. doi: 10.1016/j.celrep.2014.01.031. Epub 2014 Feb 27. Cell Rep. 2014. PMID: 24582957 Free PMC article.
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.
Mercken EM, Mitchell SJ, Martin-Montalvo A, Minor RK, Almeida M, Gomes AP, Scheibye-Knudsen M, Palacios HH, Licata JJ, Zhang Y, Becker KG, Khraiwesh H, González-Reyes JA, Villalba JM, Baur JA, Elliott P, Westphal C, Vlasuk GP, Ellis JL, Sinclair DA, Bernier M, de Cabo R. Mercken EM, et al. Among authors: mitchell sj. Aging Cell. 2014 Oct;13(5):787-96. doi: 10.1111/acel.12220. Epub 2014 Jun 16. Aging Cell. 2014. PMID: 24931715 Free PMC article.
Factors that Impact on Interrater Reliability of the Mouse Clinical Frailty Index.
Kane AE, Hilmer SN, Huizer-Pajkos A, Mach J, Nines D, Boyer D, Gavin K, Mitchell SJ, de Cabo R. Kane AE, et al. Among authors: mitchell sj. J Gerontol A Biol Sci Med Sci. 2015 Jun;70(6):694-5. doi: 10.1093/gerona/glv032. Epub 2015 Apr 2. J Gerontol A Biol Sci Med Sci. 2015. PMID: 25838548 Free PMC article. No abstract available.
Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type.
Kane AE, Mitchell SJ, Mach J, Huizer-Pajkos A, McKenzie C, Jones B, Cogger V, Le Couteur DG, de Cabo R, Hilmer SN. Kane AE, et al. Among authors: mitchell sj. Exp Gerontol. 2016 Jan;73:95-106. doi: 10.1016/j.exger.2015.11.013. Epub 2015 Nov 23. Exp Gerontol. 2016. PMID: 26615879 Free PMC article.
373 results