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Page 1
A Phase 2, Randomized, Multicenter, Placebo-Controlled, Proof-of-Concept Trial of Oral Fexinidazole in Adults With Chronic Indeterminate Chagas Disease.
Torrico F, Gascón J, Ortiz L, Pinto J, Rojas G, Palacios A, Barreira F, Blum B, Schijman AG, Vaillant M, Strub-Wourgaft N, Pinazo MJ, Bilbe G, Ribeiro I. Torrico F, et al. Among authors: ortiz l. Clin Infect Dis. 2023 Feb 8;76(3):e1186-e1194. doi: 10.1093/cid/ciac579. Clin Infect Dis. 2023. PMID: 35925555 Free PMC article. Clinical Trial.
Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial.
Torrico F, Gascon J, Ortiz L, Alonso-Vega C, Pinazo MJ, Schijman A, Almeida IC, Alves F, Strub-Wourgaft N, Ribeiro I; E1224 Study Group. Torrico F, et al. Among authors: ortiz l. Lancet Infect Dis. 2018 Apr;18(4):419-430. doi: 10.1016/S1473-3099(17)30538-8. Epub 2018 Jan 16. Lancet Infect Dis. 2018. PMID: 29352704 Free PMC article. Clinical Trial.
New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind, randomised trial.
Torrico F, Gascón J, Barreira F, Blum B, Almeida IC, Alonso-Vega C, Barboza T, Bilbe G, Correia E, Garcia W, Ortiz L, Parrado R, Ramirez JC, Ribeiro I, Strub-Wourgaft N, Vaillant M, Sosa-Estani S; BENDITA study group. Torrico F, et al. Among authors: ortiz l. Lancet Infect Dis. 2021 Aug;21(8):1129-1140. doi: 10.1016/S1473-3099(20)30844-6. Epub 2021 Apr 6. Lancet Infect Dis. 2021. PMID: 33836161 Free article. Clinical Trial.
Usefulness of Serial Blood Sampling and PCR Replicates for Treatment Monitoring of Patients with Chronic Chagas Disease.
Parrado R, Ramirez JC, de la Barra A, Alonso-Vega C, Juiz N, Ortiz L, Illanes D, Torrico F, Gascon J, Alves F, Flevaud L, Garcia L, Schijman AG, Ribeiro I. Parrado R, et al. Among authors: ortiz l. Antimicrob Agents Chemother. 2019 Jan 29;63(2):e01191-18. doi: 10.1128/AAC.01191-18. Print 2019 Feb. Antimicrob Agents Chemother. 2019. PMID: 30509941 Free PMC article. Clinical Trial.
Genetic polymorphism of Trypanosoma cruzi bloodstream populations in adult chronic indeterminate Chagas disease patients from the E1224 clinical trial.
Ramírez JC, Acevedo GR, Torres C, Parrado R, De La Barra A, Villarroel S, García L, Gascon J, Ortiz L, Torrico F, Ribeiro I, Schijman AG. Ramírez JC, et al. Among authors: ortiz l. J Antimicrob Chemother. 2022 Feb 23;77(3):578-584. doi: 10.1093/jac/dkab446. J Antimicrob Chemother. 2022. PMID: 34865002 Free PMC article. Clinical Trial.
New chemotherapy regimens and biomarkers for Chagas disease: the rationale and design of the TESEO study, an open-label, randomised, prospective, phase-2 clinical trial in the Plurinational State of Bolivia.
Alonso-Vega C, Urbina JA, Sanz S, Pinazo MJ, Pinto JJ, Gonzalez VR, Rojas G, Ortiz L, Garcia W, Lozano D, Soy D, Maldonado RA, Nagarkatti R, Debrabant A, Schijman A, Thomas MC, López MC, Michael K, Ribeiro I, Gascon J, Torrico F, Almeida IC. Alonso-Vega C, et al. Among authors: ortiz l. BMJ Open. 2021 Dec 31;11(12):e052897. doi: 10.1136/bmjopen-2021-052897. BMJ Open. 2021. PMID: 34972765 Free PMC article. Clinical Trial.
A strategy for scaling up access to comprehensive care in adults with Chagas disease in endemic countries: The Bolivian Chagas Platform.
Pinazo MJ, Pinto J, Ortiz L, Sánchez J, García W, Saravia R, Cortez MR, Moriana S, Grau E, Lozano D, Gascon J, Torrico F. Pinazo MJ, et al. Among authors: ortiz l. PLoS Negl Trop Dis. 2017 Aug 18;11(8):e0005770. doi: 10.1371/journal.pntd.0005770. eCollection 2017 Aug. PLoS Negl Trop Dis. 2017. PMID: 28820896 Free PMC article.
First external quality assurance program for bloodstream Real-Time PCR monitoring of treatment response in clinical trials of Chagas disease.
Ramírez JC, Parrado R, Sulleiro E, de la Barra A, Rodríguez M, Villarroel S, Irazu L, Alonso-Vega C, Alves F, Curto MA, García L, Ortiz L, Torrico F, Gascón J, Flevaud L, Molina I, Ribeiro I, Schijman AG. Ramírez JC, et al. Among authors: ortiz l. PLoS One. 2017 Nov 27;12(11):e0188550. doi: 10.1371/journal.pone.0188550. eCollection 2017. PLoS One. 2017. PMID: 29176887 Free PMC article.
Use of rapid diagnostic tests (RDTs) for conclusive diagnosis of chronic Chagas disease - field implementation in the Bolivian Chaco region.
Lozano D, Rojas L, Méndez S, Casellas A, Sanz S, Ortiz L, Pinazo MJ, Abril M, Gascón J, Torrico F, Alonso-Padilla J. Lozano D, et al. Among authors: ortiz l. PLoS Negl Trop Dis. 2019 Dec 19;13(12):e0007877. doi: 10.1371/journal.pntd.0007877. eCollection 2019 Dec. PLoS Negl Trop Dis. 2019. PMID: 31856247 Free PMC article.
Results and evaluation of the expansion of a model of comprehensive care for Chagas disease within the National Health System: The Bolivian Chagas network.
Pinazo MJ, Rojas-Cortez M, Saravia R, Garcia-Ruiloba W, Ramos C, Pinto Rocha JJ, Ortiz L, Castellon M, Mendoza-Claure N, Lozano D, Torrico F, Gascon J; Chagas Platform and Chagas Healthcare Network working group. Pinazo MJ, et al. Among authors: ortiz l. PLoS Negl Trop Dis. 2022 Feb 17;16(2):e0010072. doi: 10.1371/journal.pntd.0010072. eCollection 2022 Feb. PLoS Negl Trop Dis. 2022. PMID: 35176025 Free PMC article.
435 results