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IgE-neutralizing UB-221 mAb, distinct from omalizumab and ligelizumab, exhibits CD23-mediated IgE downregulation and relieves urticaria symptoms.
Kuo BS, Li CH, Chen JB, Shiung YY, Chu CY, Lee CH, Liu YJ, Kuo JH, Hsu C, Su HW, Li YF, Lai A, Ho YF, Cheng YN, Huang HX, Lung MC, Wu MS, Yang FH, Lin CH, Tseng W, Yang J, Lin CY, Tsai PH, Chang HK, Wang YJ, Chen T, Lynn S, Liao MJ, Wang CY. Kuo BS, et al. Among authors: chen jb, chen t. J Clin Invest. 2022 Aug 1;132(15):e157765. doi: 10.1172/JCI157765. J Clin Invest. 2022. PMID: 35912861 Free PMC article.
Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response.
Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. Shih HP, et al. Among authors: chen jh, chen hk, chen jb. J Exp Med. 2022 Sep 5;219(9):e20212126. doi: 10.1084/jem.20212126. Epub 2022 Jul 14. J Exp Med. 2022. PMID: 35833912 Free PMC article.
Alleles and isoforms of human membrane-bound IgA1.
Hung AF, Chen JB, Chang TW. Hung AF, et al. Among authors: chen jb. Mol Immunol. 2008 Aug;45(13):3624-30. doi: 10.1016/j.molimm.2008.04.023. Epub 2008 Jun 6. Mol Immunol. 2008. PMID: 18538846
638 results