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A multimodal iPSC platform for cystic fibrosis drug testing.
Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. Berical A, et al. Among authors: mostoslavsky g. Nat Commun. 2022 Jul 29;13(1):4270. doi: 10.1038/s41467-022-31854-8. Nat Commun. 2022. PMID: 35906215 Free PMC article.
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells.
Lafaille FG, Pessach IM, Zhang SY, Ciancanelli MJ, Herman M, Abhyankar A, Ying SW, Keros S, Goldstein PA, Mostoslavsky G, Ordovas-Montanes J, Jouanguy E, Plancoulaine S, Tu E, Elkabetz Y, Al-Muhsen S, Tardieu M, Schlaeger TM, Daley GQ, Abel L, Casanova JL, Studer L, Notarangelo LD. Lafaille FG, et al. Among authors: mostoslavsky g. Nature. 2012 Nov 29;491(7426):769-73. doi: 10.1038/nature11583. Epub 2012 Oct 28. Nature. 2012. PMID: 23103873 Free PMC article.
Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells.
Mithal A, Capilla A, Heinze D, Berical A, Villacorta-Martin C, Vedaie M, Jacob A, Abo K, Szymaniak A, Peasley M, Stuffer A, Mahoney J, Kotton DN, Hawkins F, Mostoslavsky G. Mithal A, et al. Among authors: mostoslavsky g. Nat Commun. 2020 Jan 10;11(1):215. doi: 10.1038/s41467-019-13916-6. Nat Commun. 2020. PMID: 31924806 Free PMC article.
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.
Hurley K, Ding J, Villacorta-Martin C, Herriges MJ, Jacob A, Vedaie M, Alysandratos KD, Sun YL, Lin C, Werder RB, Huang J, Wilson AA, Mithal A, Mostoslavsky G, Oglesby I, Caballero IS, Guttentag SH, Ahangari F, Kaminski N, Rodriguez-Fraticelli A, Camargo F, Bar-Joseph Z, Kotton DN. Hurley K, et al. Among authors: mostoslavsky g. Cell Stem Cell. 2020 Apr 2;26(4):593-608.e8. doi: 10.1016/j.stem.2019.12.009. Epub 2020 Jan 30. Cell Stem Cell. 2020. PMID: 32004478 Free PMC article.
Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors.
Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Abo KM, et al. Among authors: mostoslavsky g. bioRxiv [Preprint]. 2020 Jun 4:2020.06.03.132639. doi: 10.1101/2020.06.03.132639. bioRxiv. 2020. PMID: 32577635 Free PMC article. Preprint.
Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment.
Vanuytsel K, Villacorta-Martin C, Lindstrom-Vautrin J, Wang Z, Garcia-Beltran WF, Vrbanac V, Parsons D, Lam EC, Matte TM, Dowrey TW, Kumar SS, Li M, Wang F, Yeung AK, Mostoslavsky G, Dries R, Campbell JD, Belkina AC, Balazs AB, Murphy GJ. Vanuytsel K, et al. Among authors: mostoslavsky g. Nat Commun. 2022 Mar 1;13(1):1103. doi: 10.1038/s41467-022-28616-x. Nat Commun. 2022. PMID: 35232959 Free PMC article.
Ebola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes.
Scoon WA, Mancio-Silva L, Suder EL, Villacorta-Martin C, Lindstrom-Vautrin J, Bernbaum JG, Mazur S, Johnson RF, Olejnik J, Flores EY, Mithal A, Wang F, Hume AJ, Kaserman JE, March-Riera S, Wilson AA, Bhatia SN, Mühlberger E, Mostoslavsky G. Scoon WA, et al. Among authors: mostoslavsky g. Stem Cell Reports. 2022 Oct 11;17(10):2286-2302. doi: 10.1016/j.stemcr.2022.08.003. Epub 2022 Sep 8. Stem Cell Reports. 2022. PMID: 36084636 Free PMC article.
92 results