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A multimodal iPSC platform for cystic fibrosis drug testing.
Berical A, Lee RE, Lu J, Beermann ML, Le Suer JA, Mithal A, Thomas D, Ranallo N, Peasley M, Stuffer A, Bukis K, Seymour R, Harrington J, Coote K, Valley H, Hurley K, McNally P, Mostoslavsky G, Mahoney J, Randell SH, Hawkins FJ. Berical A, et al. Among authors: hurley k. Nat Commun. 2022 Jul 29;13(1):4270. doi: 10.1038/s41467-022-31854-8. Nat Commun. 2022. PMID: 35906215 Free PMC article.
Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.
Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Jacob A, et al. Among authors: hurley k. Cell Stem Cell. 2017 Oct 5;21(4):472-488.e10. doi: 10.1016/j.stem.2017.08.014. Epub 2017 Sep 28. Cell Stem Cell. 2017. PMID: 28965766 Free PMC article.
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.
Hurley K, Ding J, Villacorta-Martin C, Herriges MJ, Jacob A, Vedaie M, Alysandratos KD, Sun YL, Lin C, Werder RB, Huang J, Wilson AA, Mithal A, Mostoslavsky G, Oglesby I, Caballero IS, Guttentag SH, Ahangari F, Kaminski N, Rodriguez-Fraticelli A, Camargo F, Bar-Joseph Z, Kotton DN. Hurley K, et al. Cell Stem Cell. 2020 Apr 2;26(4):593-608.e8. doi: 10.1016/j.stem.2019.12.009. Epub 2020 Jan 30. Cell Stem Cell. 2020. PMID: 32004478 Free PMC article.
Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.
De Santi C, Fernández Fernández E, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall DC, Cutrona MB, Simpson JC, Harvey BJ, Linnane B, McNally P, Cryan SA, MacLoughlin R, Swiatecka-Urban A, Greene CM. De Santi C, et al. Among authors: hurley k. Mol Ther. 2020 Apr 8;28(4):1190-1199. doi: 10.1016/j.ymthe.2020.02.001. Epub 2020 Feb 6. Mol Ther. 2020. PMID: 32059764 Free PMC article.
An evaluation of an open access iPSC training course: "How to model interstitial lung disease using patient-derived iPSCs".
Schweikert A, Kenny S, Oglesby I, Glasgow A, de Santi C, Gensch I, Lachmann N, Desroziers T, Fletcher C, Snijders D, Nathan N, Hurley K; COST Open-ILD Group Management Committee. Schweikert A, et al. Among authors: hurley k. Stem Cell Res Ther. 2023 Dec 20;14(1):377. doi: 10.1186/s13287-023-03598-9. Stem Cell Res Ther. 2023. PMID: 38124115 Free PMC article.
A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells.
Kaserman JE, Hurley K, Dodge M, Villacorta-Martin C, Vedaie M, Jean JC, Liberti DC, James MF, Higgins MI, Lee NJ, Washko GR, San Jose Estepar R, Teckman J, Kotton DN, Wilson AA. Kaserman JE, et al. Among authors: hurley k. Stem Cell Reports. 2020 Jul 14;15(1):242-255. doi: 10.1016/j.stemcr.2020.06.006. Epub 2020 Jul 2. Stem Cell Reports. 2020. PMID: 32619491 Free PMC article.
Heterogeneity in Human Induced Pluripotent Stem Cell-derived Alveolar Epithelial Type II Cells Revealed with ABCA3/SFTPC Reporters.
Sun YL, Hurley K, Villacorta-Martin C, Huang J, Hinds A, Gopalan K, Caballero IS, Russo SJ, Kitzmiller JA, Whitsett JA, Beers MF, Kotton DN. Sun YL, et al. Among authors: hurley k. Am J Respir Cell Mol Biol. 2021 Oct;65(4):442-460. doi: 10.1165/rcmb.2020-0259OC. Am J Respir Cell Mol Biol. 2021. PMID: 34101541 Free PMC article.
A roadmap to precision treatments for familial pulmonary fibrosis.
Hurley K, Ozaki M, Philippot Q, Galvin L, Crosby D, Kirwan M, Gill DR, Alysandratos KD, Jenkins G, Griese M, Nathan N, Borie R; COST Open-ILD Group Management Committee. Hurley K, et al. EBioMedicine. 2024 May 7;104:105135. doi: 10.1016/j.ebiom.2024.105135. Online ahead of print. EBioMedicine. 2024. PMID: 38718684 Free PMC article. Review.
422 results