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Implementing a pragmatic clinical trial to tailor opioids for acute pain on behalf of the IGNITE ADOPT PGx investigators.
Clin Transl Sci. 2022 Oct;15(10):2479-2492. doi: 10.1111/cts.13376. Epub 2022 Aug 4.
Clin Transl Sci. 2022.
PMID: 35899435
Free PMC article.
Clinical Trial.
A hybrid implementation-effectiveness randomized trial of CYP2D6-guided postoperative pain management.
Thomas CD, Parvataneni HK, Gray CF, Deen JT, Prieto HA, Pulido LF, Elsey AR, Elwood EN, Starostik P, Gong Y, Fillingim RB, Johnson JA, Cavallari LH.
Thomas CD, et al. Among authors: elwood en.
Genet Med. 2021 Apr;23(4):621-628. doi: 10.1038/s41436-020-01050-4. Epub 2021 Jan 8.
Genet Med. 2021.
PMID: 33420349
Free PMC article.
Clinical Trial.
Item in Clipboard
Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network.
Ginsburg GS, Cavallari LH, Chakraborty H, Cooper-DeHoff RM, Dexter PR, Eadon MT, Ferket BS, Horowitz CR, Johnson JA, Kannry J, Kucher N, Madden EB, Orlando LA, Parker W, Peterson J, Pratt VM, Rakhra-Burris TK, Ramos MA, Skaar TC, Sperber N, Steen-Burrell KA, Van Driest SL, Voora D, Wiisanen K, Winterstein AG, Volpi S; IGNITE PTN.
Ginsburg GS, et al.
Genet Med. 2021 Jul;23(7):1185-1191. doi: 10.1038/s41436-021-01118-9. Epub 2021 Mar 29.
Genet Med. 2021.
PMID: 33782552
Free PMC article.
Clinical Trial.
Item in Clipboard
Design and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension.
Eadon MT, Cavanaugh KL, Orlando LA, Christian D, Chakraborty H, Steen-Burrell KA, Merrill P, Seo J, Hauser D, Singh R, Beasley CM, Fuloria J, Kitzman H, Parker AS, Ramos M, Ong HH, Elwood EN, Lynch SE, Clermont S, Cicali EJ, Starostik P, Pratt VM, Nguyen KA, Rosenman MB, Calman NS, Robinson M, Nadkarni GN, Madden EB, Kucher N, Volpi S, Dexter PR, Skaar TC, Johnson JA, Cooper-DeHoff RM, Horowitz CR; GUARDD-US Investigators.
Eadon MT, et al. Among authors: elwood en.
Contemp Clin Trials. 2022 Aug;119:106813. doi: 10.1016/j.cct.2022.106813. Epub 2022 Jun 1.
Contemp Clin Trials. 2022.
PMID: 35660539
Free PMC article.
Clinical Trial.
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