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Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life.
Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Kojonazarov B, Klymenko O, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Seeger W, Dötsch J, Pullamsetti SS, Alejandre Alcazar MA. Selle J, et al. Among authors: mahabir e. Nat Commun. 2022 Jul 27;13(1):4352. doi: 10.1038/s41467-022-31655-z. Nat Commun. 2022. PMID: 35896539 Free PMC article.
Maternal obesity attenuates predelivery inflammatory reaction in C57BL/6N mice.
Appel S, Schulze-Edinghausen M, Kretschmer T, Storck S, Janoschek R, Bae-Gartz I, Handwerk M, Wohlfarth M, Nüsken KD, Hucklenbruch-Rother E, Heykants M, Mahabir E, Dötsch J. Appel S, et al. Among authors: mahabir e. J Reprod Immunol. 2017 Aug;122:10-13. doi: 10.1016/j.jri.2017.06.004. Epub 2017 Jul 1. J Reprod Immunol. 2017. PMID: 28719804
Exercise during pregnancy and its impact on mothers and offspring in humans and mice.
Ferrari N, Bae-Gartz I, Bauer C, Janoschek R, Koxholt I, Mahabir E, Appel S, Alejandre Alcazar MA, Grossmann N, Vohlen C, Brockmeier K, Dötsch J, Hucklenbruch-Rother E, Graf C. Ferrari N, et al. Among authors: mahabir e. J Dev Orig Health Dis. 2018 Feb;9(1):63-76. doi: 10.1017/S2040174417000617. Epub 2017 Aug 7. J Dev Orig Health Dis. 2018. PMID: 28780912
Maternal Exercise Mediates Hepatic Metabolic Programming via Activation of AMPK-PGC1α Axis in the Offspring of Obese Mothers.
Kasper P, Breuer S, Hoffmann T, Vohlen C, Janoschek R, Schmitz L, Appel S, Fink G, Hünseler C, Quaas A, Demir M, Lang S, Steffen HM, Martin A, Schramm C, Bürger M, Mahabir E, Goeser T, Dötsch J, Hucklenbruch-Rother E, Bae-Gartz I. Kasper P, et al. Among authors: mahabir e. Cells. 2021 May 19;10(5):1247. doi: 10.3390/cells10051247. Cells. 2021. PMID: 34069390 Free PMC article.
Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring.
Breuer S, Kasper P, Vohlen C, Janoschek R, Hoffmann T, Appel S, Müller-Limberger E, Mesaros A, Rose-John S, Garbers C, Müller S, Lackmann JW, Mahabir E, Dötsch J, Hucklenbruch-Rother E, Bae-Gartz I. Breuer S, et al. Among authors: mahabir e. Nutrients. 2021 Oct 23;13(11):3735. doi: 10.3390/nu13113735. Nutrients. 2021. PMID: 34835991 Free PMC article.
Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations.
Macheleidt IF, Dalvi PS, Lim SY, Meemboor S, Meder L, Käsgen O, Müller M, Kleemann K, Wang L, Nürnberg P, Rüsseler V, Schäfer SC, Mahabir E, Büttner R, Odenthal M. Macheleidt IF, et al. Among authors: mahabir e. Mol Oncol. 2018 Nov;12(11):1965-1979. doi: 10.1002/1878-0261.12382. Epub 2018 Oct 13. Mol Oncol. 2018. PMID: 30220105 Free PMC article.
Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion.
Yu X, Elfimova N, Müller M, Bachurski D, Koitzsch U, Drebber U, Mahabir E, Hansen HP, Friedman SL, Klein S, Dienes HP, Hösel M, Buettner R, Trebicka J, Kondylis V, Mannaerts I, Odenthal M. Yu X, et al. Among authors: mahabir e. Cell Mol Gastroenterol Hepatol. 2022;13(6):1701-1716. doi: 10.1016/j.jcmgh.2022.02.013. Epub 2022 Feb 24. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35219894 Free PMC article.
48 results