Al-Karmalawy AA - Search Results

1

Insight into Genetic Characteristics of Identified SARS-CoV-2 Variants in Egypt from March 2020 to May 2021.

Roshdy WH, Kandeil A, El-Shesheny R, Khalifa MK, Al-Karmalawy AA, Showky S, Naguib A, Elguindy N, Fahim M, Abu Elsood H, El Taweel A, Salamony A, Mohsen A, Kayali G, Ali MA, Kandeel A. Roshdy WH, et al. Pathogens. 2022 Jul 26;11(8):834. doi: 10.3390/pathogens11080834. Pathogens. 2022. PMID: 35894057 Free PMC article.

2

4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments.

Ragab MA, Eldehna WM, Nocentini A, Bonardi A, Okda HE, Elgendy B, Ibrahim TS, Abd-Alhaseeb MM, Gratteri P, Supuran CT, Al-Karmalawy AA, Elagawany M. Ragab MA, et al. Eur J Med Chem. 2023 Mar 15;250:115180. doi: 10.1016/j.ejmech.2023.115180. Epub 2023 Feb 3. Eur J Med Chem. 2023. PMID: 36796297

3

Novel Hybrid Indole-Based Caffeic Acid Amide Derivatives as Potent Free Radical Scavenging Agents: Rational Design, Synthesis, Spectroscopic Characterization, In Silico and In Vitro Investigations.

Elkamhawy A, Oh NK, Gouda NA, Abdellattif MH, Alshammari SO, Abourehab MAS, Alshammari QA, Belal A, Kim M, Al-Karmalawy AA, Lee K. Elkamhawy A, et al. Metabolites. 2023 Jan 17;13(2):141. doi: 10.3390/metabo13020141. Metabolites. 2023. PMID: 36837759 Free PMC article.

4

Investigation of the phytochemical composition, antioxidant, antibacterial, anti-osteoarthritis, and wound healing activities of selected vegetable waste.

Salem MA, Mohamed OG, Mosalam EM, Elberri AI, Abdel-Bar HM, Hassan M, Al-Karmalawy AA, Tripathi A, Ezzat SM, Abo Mansour HE. Salem MA, et al. Sci Rep. 2023 Aug 10;13(1):13034. doi: 10.1038/s41598-023-38591-y. Sci Rep. 2023. PMID: 37563154 Free PMC article.

5

Experimental design of D-α-tocopherol polyethylene glycol 1000 succinate stabilized bile salt based Nano-vesicles for improved cytotoxicity and bioavailability of colchicine binding site inhibitor Candidates: In Vitro, in silico, and pharmacokinetic studies.

Abo Elmaaty A, Al-Karmalawy AA, Nafie MS, Shamaa MM, Zaki I, Alnajjar R, Zakaria MY. Abo Elmaaty A, et al. Int J Pharm. 2023 Jun 10;640:122980. doi: 10.1016/j.ijpharm.2023.122980. Epub 2023 Apr 26. Int J Pharm. 2023. PMID: 37116601

6

Development of new TAK-285 derivatives as potent EGFR/HER2 inhibitors possessing antiproliferative effects against 22RV1 and PC3 prostate carcinoma cell lines.

Son S, Elkamhawy A, Gul AR, Al-Karmalawy AA, Alnajjar R, Abdeen A, Ibrahim SF, Alshammari SO, Alshammari QA, Choi WJ, Park TJ, Lee K. Son S, et al. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2202358. doi: 10.1080/14756366.2023.2202358. J Enzyme Inhib Med Chem. 2023. PMID: 37096560 Free PMC article.

7

Molecular docking, molecular dynamics, and in vitro studies reveal the potential of angiotensin II receptor blockers to inhibit the COVID-19 main protease.

Alnajjar R, Mostafa A, Kandeil A, Al-Karmalawy AA. Alnajjar R, et al. Heliyon. 2020 Dec;6(12):e05641. doi: 10.1016/j.heliyon.2020.e05641. Epub 2020 Dec 3. Heliyon. 2020. PMID: 33294721 Free PMC article.

8

Strong Inhibitory Activity and Action Modes of Synthetic Maslinic Acid Derivative on Highly Pathogenic Coronaviruses: COVID-19 Drug Candidate.

Soltane R, Chrouda A, Mostafa A, Al-Karmalawy AA, Chouaïb K, Dhahri A, Pashameah RA, Alasiri A, Kutkat O, Shehata M, Jannet HB, Gharbi J, Ali MA. Soltane R, et al. Pathogens. 2021 May 19;10(5):623. doi: 10.3390/pathogens10050623. Pathogens. 2021. PMID: 34069460 Free PMC article.

9

Bioactive Polyphenolic Compounds Showing Strong Antiviral Activities against Severe Acute Respiratory Syndrome Coronavirus 2.

Kandeil A, Mostafa A, Kutkat O, Moatasim Y, Al-Karmalawy AA, Rashad AA, Kayed AE, Kayed AE, El-Shesheny R, Kayali G, Ali MA. Kandeil A, et al. Pathogens. 2021 Jun 15;10(6):758. doi: 10.3390/pathogens10060758. Pathogens. 2021. PMID: 34203977 Free PMC article.

10

Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies.

Mahmoud A, Mostafa A, Al-Karmalawy AA, Zidan A, Abulkhair HS, Mahmoud SH, Shehata M, Elhefnawi MM, Ali MA. Mahmoud A, et al. Heliyon. 2021 Sep;7(9):e07962. doi: 10.1016/j.heliyon.2021.e07962. Epub 2021 Sep 9. Heliyon. 2021. PMID: 34518806 Free PMC article.

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