Amporndanai K - Search Results - PubMed

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10 results

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Page 1

1

Targeting the Ubiquinol-Reduction (Q_i) Site of the Mitochondrial Cytochrome bc₁ Complex for the Development of Next Generation Quinolone Antimalarials.

Amporndanai K, Pinthong N, O'Neill PM, Hong WD, Amewu RK, Pidathala C, Berry NG, Leung SC, Ward SA, Biagini GA, Hasnain SS, Antonyuk SV. Amporndanai K, et al. Biology (Basel). 2022 Jul 25;11(8):1109. doi: 10.3390/biology11081109. Biology (Basel). 2022. PMID: 35892964 Free PMC article.

2

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc₁ complexes for structure-based drug discovery.

Amporndanai K, Johnson RM, O'Neill PM, Fishwick CWG, Jamson AH, Rawson S, Muench SP, Hasnain SS, Antonyuk SV. Amporndanai K, et al. IUCrJ. 2018 Feb 20;5(Pt 2):200-210. doi: 10.1107/S2052252518001616. eCollection 2018 Mar 1. IUCrJ. 2018. PMID: 29765610 Free PMC article.

3

Potent Antimalarial 2-Pyrazolyl Quinolone bc ₁ (Q_i) Inhibitors with Improved Drug-like Properties.

David Hong W, Leung SC, Amporndanai K, Davies J, Priestley RS, Nixon GL, Berry NG, Samar Hasnain S, Antonyuk S, Ward SA, Biagini GA, O'Neill PM. David Hong W, et al. Among authors: amporndanai k. ACS Med Chem Lett. 2018 Oct 19;9(12):1205-1210. doi: 10.1021/acsmedchemlett.8b00371. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613327 Free PMC article.

4

Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy.

Chantadul V, Wright GSA, Amporndanai K, Shahid M, Antonyuk SV, Washbourn G, Rogers M, Roberts N, Pye M, O'Neill PM, Hasnain SS. Chantadul V, et al. Among authors: amporndanai k. Commun Biol. 2020 Mar 5;3(1):97. doi: 10.1038/s42003-020-0826-3. Commun Biol. 2020. PMID: 32139772 Free PMC article.

5

Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.

Amporndanai K, Rogers M, Watanabe S, Yamanaka K, O'Neill PM, Hasnain SS. Amporndanai K, et al. EBioMedicine. 2020 Sep;59:102980. doi: 10.1016/j.ebiom.2020.102980. Epub 2020 Aug 30. EBioMedicine. 2020. PMID: 32862101 Free PMC article.

6

Purification and Structural Characterization of Aggregation-Prone Human TDP-43 Involved in Neurodegenerative Diseases.

Wright GSA, Watanabe TF, Amporndanai K, Plotkin SS, Cashman NR, Antonyuk SV, Hasnain SS. Wright GSA, et al. Among authors: amporndanai k. iScience. 2020 Jun 26;23(6):101159. doi: 10.1016/j.isci.2020.101159. Epub 2020 May 15. iScience. 2020. PMID: 32480125 Free PMC article.

7

Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.

McPhillie MJ, Zhou Y, Hickman MR, Gordon JA, Weber CR, Li Q, Lee PJ, Amporndanai K, Johnson RM, Darby H, Woods S, Li ZH, Priestley RS, Ristroph KD, Biering SB, El Bissati K, Hwang S, Hakim FE, Dovgin SM, Lykins JD, Roberts L, Hargrave K, Cong H, Sinai AP, Muench SP, Dubey JP, Prud'homme RK, Lorenzi HA, Biagini GA, Moreno SN, Roberts CW, Antonyuk SV, Fishwick CWG, McLeod R. McPhillie MJ, et al. Among authors: amporndanai k. Front Cell Infect Microbiol. 2020 Jun 9;10:203. doi: 10.3389/fcimb.2020.00203. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32626661 Free PMC article.

8

Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives.

Amporndanai K, Meng X, Shang W, Jin Z, Rogers M, Zhao Y, Rao Z, Liu ZJ, Yang H, Zhang L, O'Neill PM, Samar Hasnain S. Amporndanai K, et al. Nat Commun. 2021 May 24;12(1):3061. doi: 10.1038/s41467-021-23313-7. Nat Commun. 2021. PMID: 34031399 Free PMC article.

9

Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement.

Watanabe S, Amporndanai K, Awais R, Latham C, Awais M, O'Neill PM, Yamanaka K, Hasnain SS. Watanabe S, et al. Among authors: amporndanai k. Sci Rep. 2024 May 27;14(1):12118. doi: 10.1038/s41598-024-62903-5. Sci Rep. 2024. PMID: 38802492 Free PMC article.

10

Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors.

Teuscher KB, Mills JJ, Tian J, Han C, Meyers KM, Sai J, South TM, Crow MM, Van Meveren M, Sensintaffar JL, Zhao B, Amporndanai K, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW. Teuscher KB, et al. Among authors: amporndanai k. J Med Chem. 2023 Dec 28;66(24):16783-16806. doi: 10.1021/acs.jmedchem.3c01529. Epub 2023 Dec 12. J Med Chem. 2023. PMID: 38085679

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