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Hybridization Approach to Identify Salicylanilides as Inhibitors of Tubulin Polymerization and Signal Transducers and Activators of Transcription 3 (STAT3).
Pharmaceuticals (Basel). 2022 Jul 6;15(7):835. doi: 10.3390/ph15070835.
Pharmaceuticals (Basel). 2022.
PMID: 35890135
Free PMC article.
Inhibition of XPO-1 Mediated Nuclear Export through the Michael-Acceptor Character of Chalcones.
Gargantilla M, López-Fernández J, Camarasa MJ, Persoons L, Daelemans D, Priego EM, Pérez-Pérez MJ.
Gargantilla M, et al.
Pharmaceuticals (Basel). 2021 Nov 6;14(11):1131. doi: 10.3390/ph14111131.
Pharmaceuticals (Basel). 2021.
PMID: 34832913
Free PMC article.
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Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop.
Bueno O, Gargantilla M, Estévez-Gallego J, Martins S, Díaz JF, Camarasa MJ, Liekens S, Pérez-Pérez MJ, Priego EM.
Bueno O, et al. Among authors: gargantilla m.
Eur J Med Chem. 2019 Jun 1;171:195-208. doi: 10.1016/j.ejmech.2019.03.045. Epub 2019 Mar 21.
Eur J Med Chem. 2019.
PMID: 30921759
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Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia.
Quaglio D, Zhdanovskaya N, Tobajas G, Cuartas V, Balducci S, Christodoulou MS, Fabrizi G, Gargantilla M, Priego EM, Carmona Pestaña Á, Passarella D, Screpanti I, Botta B, Palermo R, Mori M, Ghirga F, Pérez-Pérez MJ.
Quaglio D, et al. Among authors: gargantilla m.
ACS Med Chem Lett. 2019 Feb 26;10(4):639-643. doi: 10.1021/acsmedchemlett.8b00608. eCollection 2019 Apr 11.
ACS Med Chem Lett. 2019.
PMID: 30996810
Free PMC article.
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Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.
Bort A, Quesada S, Ramos-Torres Á, Gargantilla M, Priego EM, Raynal S, Lepifre F, Gasalla JM, Rodriguez-Henche N, Castro A, Díaz-Laviada I.
Bort A, et al. Among authors: gargantilla m.
Sci Rep. 2018 Mar 12;8(1):4370. doi: 10.1038/s41598-018-22690-2.
Sci Rep. 2018.
PMID: 29531259
Free PMC article.
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C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
Gargantilla M, Francés C, Adhav A, Forcada-Nadal A, Martínez-Gualda B, Martí-Marí O, López-Redondo ML, Melero R, Marco-Marín C, Gougeard N, Espinosa C, Rubio-Del-Campo A, Ruiz-Partida R, Hernández-Sierra MDP, Villamayor-Belinchón L, Bravo J, Llacer JL, Marina A, Rubio V, San-Félix A, Geller R, Pérez-Pérez MJ.
Gargantilla M, et al.
J Med Chem. 2023 Aug 10;66(15):10432-10457. doi: 10.1021/acs.jmedchem.3c00576. Epub 2023 Jul 20.
J Med Chem. 2023.
PMID: 37471688
Free PMC article.
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