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Direct sGC activation bypasses NO scavenging reactions of intravascular free oxy-hemoglobin and limits vasoconstriction.
Raat NJ, Tabima DM, Specht PA, Tejero J, Champion HC, Kim-Shapiro DB, Baust J, Mik EG, Hildesheim M, Stasch JP, Becker EM, Truebel H, Gladwin MT. Raat NJ, et al. Among authors: mik eg. Antioxid Redox Signal. 2013 Dec 20;19(18):2232-43. doi: 10.1089/ars.2013.5181. Epub 2013 Jul 9. Antioxid Redox Signal. 2013. PMID: 23697678 Free PMC article.
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