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Telomere, telomerase and liver disease.
Aravinthan AD, Alexander GJ. Aravinthan AD, et al. Among authors: alexander gj. Liver Int. 2018 Jan;38(1):33-34. doi: 10.1111/liv.13630. Liver Int. 2018. PMID: 29272567 No abstract available.
TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.
Liu YL, Reeves HL, Burt AD, Tiniakos D, McPherson S, Leathart JB, Allison ME, Alexander GJ, Piguet AC, Anty R, Donaldson P, Aithal GP, Francque S, Van Gaal L, Clement K, Ratziu V, Dufour JF, Day CP, Daly AK, Anstee QM. Liu YL, et al. Among authors: alexander gj. Nat Commun. 2014 Jun 30;5:4309. doi: 10.1038/ncomms5309. Nat Commun. 2014. PMID: 24978903 Free PMC article.
Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis.
Owen NE, Alexander GJ, Sen S, Bunclark K, Polwarth G, Pepke-Zaba J, Davenport AP, Morrell NW, Upton PD. Owen NE, et al. Among authors: alexander gj. EBioMedicine. 2020 Jun;56:102794. doi: 10.1016/j.ebiom.2020.102794. Epub 2020 May 23. EBioMedicine. 2020. PMID: 32454407 Free PMC article.
The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort.
Pells G, Mells GF, Carbone M, Newton JL, Bathgate AJ, Burroughs AK, Heneghan MA, Neuberger JM, Day DB, Ducker SJ; UK-PBC Consortium; Sandford RN, Alexander GJ, Jones DE. Pells G, et al. Among authors: alexander gj. J Hepatol. 2013 Jul;59(1):67-73. doi: 10.1016/j.jhep.2013.02.019. Epub 2013 Mar 4. J Hepatol. 2013. PMID: 23466308 Free PMC article.
Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score.
Carbone M, Nardi A, Flack S, Carpino G, Varvaropoulou N, Gavrila C, Spicer A, Badrock J, Bernuzzi F, Cardinale V, Ainsworth HF, Heneghan MA, Thorburn D, Bathgate A, Jones R, Neuberger JM, Battezzati PM, Zuin M, Taylor-Robinson S, Donato MF, Kirby J, Mitchell-Thain R, Floreani A, Sampaziotis F, Muratori L, Alvaro D, Marzioni M, Miele L, Marra F, Giannini E, Gaudio E, Ronca V, Bonato G, Cristoferi L, Malinverno F, Gerussi A, Stocken DD, Cordell HJ, Hirschfield GM, Alexander GJ, Sandford RN, Jones DE, Invernizzi P, Mells GF; Italian PBC Study Group and the UK–PBC Consortium. Carbone M, et al. Among authors: alexander gj. Lancet Gastroenterol Hepatol. 2018 Sep;3(9):626-634. doi: 10.1016/S2468-1253(18)30163-8. Epub 2018 Jul 13. Lancet Gastroenterol Hepatol. 2018. PMID: 30017646 Free PMC article.
BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial.
Hegade VS, Kendrick SF, Dobbins RL, Miller SR, Richards D, Storey J, Dukes G, Gilchrist K, Vallow S, Alexander GJ, Corrigan M, Hirschfield GM, Jones DE. Hegade VS, et al. Among authors: alexander gj. BMC Gastroenterol. 2016 Jul 19;16(1):71. doi: 10.1186/s12876-016-0481-9. BMC Gastroenterol. 2016. PMID: 27431238 Free PMC article. Clinical Trial.
Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation.
Sampaziotis F, de Brito MC, Madrigal P, Bertero A, Saeb-Parsy K, Soares FAC, Schrumpf E, Melum E, Karlsen TH, Bradley JA, Gelson WT, Davies S, Baker A, Kaser A, Alexander GJ, Hannan NRF, Vallier L. Sampaziotis F, et al. Among authors: alexander gj. Nat Biotechnol. 2015 Aug;33(8):845-852. doi: 10.1038/nbt.3275. Epub 2015 Jul 13. Nat Biotechnol. 2015. PMID: 26167629 Free PMC article.
385 results