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Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.
Chen C, Saville JW, Marti MM, Schäfer A, Cheng MH, Mannar D, Zhu X, Berezuk AM, Banerjee A, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Enick N, McCormick KD, Liu X, Adams C, Hines MG, Sun Z, Chen W, Jacobs JL, Barratt-Boyes SM, Mellors JW, Baric RS, Bahar I, Dimitrov DS, Subramaniam S, Martinez DR, Li W. Chen C, et al. Among authors: chen w. iScience. 2022 Aug 19;25(8):104798. doi: 10.1016/j.isci.2022.104798. Epub 2022 Jul 20. iScience. 2022. PMID: 35875685 Free PMC article.
Construction of a human antibody domain (VH) library.
Chen W, Zhu Z, Xiao X, Dimitrov DS. Chen W, et al. Methods Mol Biol. 2009;525:81-99, xiii. doi: 10.1007/978-1-59745-554-1_4. Methods Mol Biol. 2009. PMID: 19252835 Free PMC article.
Candidate antibody-based therapeutics against HIV-1.
Gong R, Chen W, Dimitrov DS. Gong R, et al. Among authors: chen w. BioDrugs. 2012 Jun 1;26(3):143-62. doi: 10.2165/11631400-000000000-00000. BioDrugs. 2012. PMID: 22462520 Free PMC article. Review.
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