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The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells.
Ikeda H, Taira N, Hara F, Fujita T, Yamamoto H, Soh J, Toyooka S, Nogami T, Shien T, Doihara H, Miyoshi S. Ikeda H, et al. Among authors: shien t. Breast Cancer Res. 2010;12(3):R43. doi: 10.1186/bcr2598. Epub 2010 Jun 28. Breast Cancer Res. 2010. PMID: 20579400 Free PMC article.
Combination treatment with fulvestrant and various cytotoxic agents (doxorubicin, paclitaxel, docetaxel, vinorelbine, and 5-fluorouracil) has a synergistic effect in estrogen receptor-positive breast cancer.
Ikeda H, Taira N, Nogami T, Shien K, Okada M, Shien T, Doihara H, Miyoshi S. Ikeda H, et al. Among authors: shien k, shien t. Cancer Sci. 2011 Nov;102(11):2038-42. doi: 10.1111/j.1349-7006.2011.02050.x. Epub 2011 Sep 1. Cancer Sci. 2011. PMID: 21801281 Free article.
DNA methylation status of REIC/Dkk-3 gene in human malignancies.
Hayashi T, Asano H, Toyooka S, Tsukuda K, Soh J, Shien T, Taira N, Maki Y, Tanaka N, Doihara H, Nasu Y, Huh NH, Miyoshi S. Hayashi T, et al. Among authors: shien t. J Cancer Res Clin Oncol. 2012 May;138(5):799-809. doi: 10.1007/s00432-012-1158-6. Epub 2012 Jan 25. J Cancer Res Clin Oncol. 2012. PMID: 22274868 Free PMC article.
Study about the Efficacy of Metformin to Immune Function in Cancer Patients.
Watanabe M, Yamamoto H, Eikawa S, Shien K, Shien T, Soh J, Hotta K, Wada J, Hinotsu S, Fujiwara T, Kiura K, Doihara H, Miyoshi S, Udono H, Toyooka S. Watanabe M, et al. Among authors: shien k, shien t. Acta Med Okayama. 2016 Aug;70(4):327-30. doi: 10.18926/AMO/54514. Acta Med Okayama. 2016. PMID: 27549683 Free article.
Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer.
Sato H, Yamamoto H, Sakaguchi M, Shien K, Tomida S, Shien T, Ikeda H, Hatono M, Torigoe H, Namba K, Yoshioka T, Kurihara E, Ogoshi Y, Takahashi Y, Soh J, Toyooka S. Sato H, et al. Among authors: shien k, shien t. Cancer Sci. 2018 Oct;109(10):3183-3196. doi: 10.1111/cas.13763. Epub 2018 Sep 14. Cancer Sci. 2018. PMID: 30098066 Free PMC article.
149 results