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Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7.
Chen J, Zhao Y, Zhang F, Li J, Boland JA, Cheng NC, Liu K, Tiffen JC, Bertolino P, Bowen DG, Krueger A, Lisowski L, Alexander IE, Vadas MA, El-Omar E, Gamble JR, McCaughan GW. Chen J, et al. Among authors: alexander ie. Cell Mol Life Sci. 2022 Jul 22;79(8):443. doi: 10.1007/s00018-022-04452-6. Cell Mol Life Sci. 2022. PMID: 35867177 Free PMC article.
Gene therapy in transplantation.
Laurence JM, Allen RD, McCaughan GW, Logan GJ, Alexander IE, Bishop GA, Sharland AF. Laurence JM, et al. Among authors: alexander ie. Transplant Rev (Orlando). 2009 Jul;23(3):159-70. doi: 10.1016/j.trre.2009.04.001. Epub 2009 May 9. Transplant Rev (Orlando). 2009. PMID: 19428235 Review.
Gene therapy for tolerance: high-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin grafts.
Cunningham EC, Tay SS, Wang C, Rtshiladze M, Wang ZZ, McGuffog C, Cubitt J, McCaughan GW, Alexander IE, Bertolino P, Sharland AF, Bowen DG, Bishop GA. Cunningham EC, et al. Among authors: alexander ie. Transplantation. 2013 Jan 15;95(1):70-7. doi: 10.1097/TP.0b013e318278d39a. Transplantation. 2013. PMID: 23263501
Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses.
Tay SS, Wong YC, McDonald DM, Wood NA, Roediger B, Sierro F, Mcguffog C, Alexander IE, Bishop GA, Gamble JR, Weninger W, McCaughan GW, Bertolino P, Bowen DG. Tay SS, et al. Among authors: alexander ie. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2540-9. doi: 10.1073/pnas.1406674111. Epub 2014 Jun 10. Proc Natl Acad Sci U S A. 2014. PMID: 24927525 Free PMC article.
Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.
Tay SS, Wong YC, Roediger B, Sierro F, Lu B, McDonald DM, McGuffog CM, Meyer NJ, Alexander IE, Parish IA, Heath WR, Weninger W, Bishop GA, Gamble JR, McCaughan GW, Bertolino P, Bowen DG. Tay SS, et al. Among authors: alexander ie. J Immunol. 2014 Sep 1;193(5):2087-95. doi: 10.4049/jimmunol.1400037. Epub 2014 Jul 28. J Immunol. 2014. PMID: 25070847
Adeno-associated virus serotypes for gene therapeutics.
Lisowski L, Tay SS, Alexander IE. Lisowski L, et al. Among authors: alexander ie. Curr Opin Pharmacol. 2015 Oct;24:59-67. doi: 10.1016/j.coph.2015.07.006. Epub 2015 Aug 25. Curr Opin Pharmacol. 2015. PMID: 26291407 Review.
Identification of liver-specific enhancer-promoter activity in the 3' untranslated region of the wild-type AAV2 genome.
Logan GJ, Dane AP, Hallwirth CV, Smyth CM, Wilkie EE, Amaya AK, Zhu E, Khandekar N, Ginn SL, Liao SHY, Cunningham SC, Sasaki N, Cabanes-Creus M, Tam PPL, Russell DW, Lisowski L, Alexander IE. Logan GJ, et al. Among authors: alexander ie. Nat Genet. 2017 Aug;49(8):1267-1273. doi: 10.1038/ng.3893. Epub 2017 Jun 19. Nat Genet. 2017. PMID: 28628105
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Among authors: alexander ie. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.
185 results