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Cooperative Targets of Combined mTOR/HDAC Inhibition Promote MYC Degradation.
Simmons JK, Michalowski AM, Gamache BJ, DuBois W, Patel J, Zhang K, Gary J, Zhang S, Gaikwad S, Connors D, Watson N, Leon E, Chen JQ, Kuehl WM, Lee MP, Zingone A, Landgren O, Ordentlich P, Huang J, Mock BA. Simmons JK, et al. Among authors: huang j. Mol Cancer Ther. 2017 Sep;16(9):2008-2021. doi: 10.1158/1535-7163.MCT-17-0171. Epub 2017 May 18. Mol Cancer Ther. 2017. PMID: 28522584 Free PMC article.
p53 loss increases the osteogenic differentiation of bone marrow stromal cells.
He Y, de Castro LF, Shin MH, Dubois W, Yang HH, Jiang S, Mishra PJ, Ren L, Gou H, Lal A, Khanna C, Merlino G, Lee M, Robey PG, Huang J. He Y, et al. Among authors: huang j. Stem Cells. 2015 Apr;33(4):1304-19. doi: 10.1002/stem.1925. Stem Cells. 2015. PMID: 25524638 Free PMC article.
iPSCs are safe!
Yan H, Shi YB, Huang J. Yan H, et al. Among authors: huang j. Cell Biosci. 2017 May 30;7:30. doi: 10.1186/s13578-017-0157-3. eCollection 2017. Cell Biosci. 2017. PMID: 28572916 Free PMC article.
G9a and Glp methylate lysine 373 in the tumor suppressor p53.
Huang J, Dorsey J, Chuikov S, Zhang X, Jenuwein T, Reinberg D, Berger SL. Huang J, et al. J Biol Chem. 2010 Mar 26;285(13):9636-9641. doi: 10.1074/jbc.M109.062588. Epub 2010 Jan 29. J Biol Chem. 2010. PMID: 20118233 Free PMC article.
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