Garcia KC - Search Results

1

Organizing structural principles of the IL-17 ligand-receptor axis.

Wilson SC, Caveney NA, Yen M, Pollmann C, Xiang X, Jude KM, Hafer M, Tsutsumi N, Piehler J, Garcia KC. Wilson SC, et al. Among authors: garcia kc. Nature. 2022 Sep;609(7927):622-629. doi: 10.1038/s41586-022-05116-y. Epub 2022 Jul 21. Nature. 2022. PMID: 35863378 Free PMC article.

2

Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor.

Skiniotis G, Boulanger MJ, Garcia KC, Walz T. Skiniotis G, et al. Among authors: garcia kc. Nat Struct Mol Biol. 2005 Jun;12(6):545-51. doi: 10.1038/nsmb941. Epub 2005 May 15. Nat Struct Mol Biol. 2005. PMID: 15895091

3

Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'.

Feng D, Bond CJ, Ely LK, Maynard J, Garcia KC. Feng D, et al. Among authors: garcia kc. Nat Immunol. 2007 Sep;8(9):975-83. doi: 10.1038/ni1502. Epub 2007 Aug 12. Nat Immunol. 2007. PMID: 17694060

4

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC. LaPorte SL, et al. Among authors: garcia kc. Cell. 2008 Jan 25;132(2):259-72. doi: 10.1016/j.cell.2007.12.030. Cell. 2008. PMID: 18243101 Free PMC article.

5

Structural biology of shared cytokine receptors.

Wang X, Lupardus P, Laporte SL, Garcia KC. Wang X, et al. Among authors: garcia kc. Annu Rev Immunol. 2009;27:29-60. doi: 10.1146/annurev.immunol.24.021605.090616. Annu Rev Immunol. 2009. PMID: 18817510 Free PMC article. Review.

6

Structural basis of receptor sharing by interleukin 17 cytokines.

Ely LK, Fischer S, Garcia KC. Ely LK, et al. Among authors: garcia kc. Nat Immunol. 2009 Dec;10(12):1245-51. doi: 10.1038/ni.1813. Epub 2009 Oct 18. Nat Immunol. 2009. PMID: 19838198 Free PMC article.

7

Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Rα cytokine receptor complex, and the receptor-Jak1 holocomplex.

Lupardus PJ, Skiniotis G, Rice AJ, Thomas C, Fischer S, Walz T, Garcia KC. Lupardus PJ, et al. Among authors: garcia kc. Structure. 2011 Jan 12;19(1):45-55. doi: 10.1016/j.str.2010.10.010. Structure. 2011. PMID: 21220115 Free PMC article.

8

Structural linkage between ligand discrimination and receptor activation by type I interferons.

Thomas C, Moraga I, Levin D, Krutzik PO, Podoplelova Y, Trejo A, Lee C, Yarden G, Vleck SE, Glenn JS, Nolan GP, Piehler J, Schreiber G, Garcia KC. Thomas C, et al. Among authors: garcia kc. Cell. 2011 Aug 19;146(4):621-32. doi: 10.1016/j.cell.2011.06.048. Cell. 2011. PMID: 21854986 Free PMC article.

9

Structure of the activating IL-1 receptor signaling complex.

Thomas C, Bazan JF, Garcia KC. Thomas C, et al. Among authors: garcia kc. Nat Struct Mol Biol. 2012 Mar 18;19(4):455-7. doi: 10.1038/nsmb.2260. Nat Struct Mol Biol. 2012. PMID: 22426547 Free PMC article.

10

Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'.

Levin AM, Bates DL, Ring AM, Krieg C, Lin JT, Su L, Moraga I, Raeber ME, Bowman GR, Novick P, Pande VS, Fathman CG, Boyman O, Garcia KC. Levin AM, et al. Among authors: garcia kc. Nature. 2012 Mar 25;484(7395):529-33. doi: 10.1038/nature10975. Nature. 2012. PMID: 22446627 Free PMC article.

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