Tolbert WD - Search Results

1

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.

Chen Y, Sun L, Ullah I, Beaudoin-Bussières G, Anand SP, Hederman AP, Tolbert WD, Sherburn R, Nguyen DN, Marchitto L, Ding S, Wu D, Luo Y, Gottumukkala S, Moran S, Kumar P, Piszczek G, Mothes W, Ackerman ME, Finzi A, Uchil PD, Gonzalez FJ, Pazgier M. Chen Y, et al. Among authors: tolbert wd. Sci Adv. 2022 Jul 15;8(28):eabn4188. doi: 10.1126/sciadv.abn4188. Epub 2022 Jul 13. Sci Adv. 2022. PMID: 35857504 Free PMC article.

2

Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.

Tolbert WD, Gohain N, Veillette M, Chapleau JP, Orlandi C, Visciano ML, Ebadi M, DeVico AL, Fouts TR, Finzi A, Lewis GK, Pazgier M. Tolbert WD, et al. Structure. 2016 May 3;24(5):697-709. doi: 10.1016/j.str.2016.03.005. Epub 2016 Mar 31. Structure. 2016. PMID: 27041594 Free PMC article.

3

A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability.

Ding S, Tolbert WD, Prévost J, Pacheco B, Coutu M, Debbeche O, Xiang SH, Pazgier M, Finzi A. Ding S, et al. Among authors: tolbert wd. J Virol. 2016 Sep 12;90(19):8395-409. doi: 10.1128/JVI.01068-16. Print 2016 Oct 1. J Virol. 2016. PMID: 27384653 Free PMC article.

4

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.

Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A. Richard J, et al. Among authors: tolbert wd. EBioMedicine. 2016 Oct;12:208-218. doi: 10.1016/j.ebiom.2016.09.004. Epub 2016 Sep 9. EBioMedicine. 2016. PMID: 27633463 Free PMC article.

5

Molecular basis for epitope recognition by non-neutralizing anti-gp41 antibody F240.

Gohain N, Tolbert WD, Orlandi C, Richard J, Ding S, Chen X, Bonsor DA, Sundberg EJ, Lu W, Ray K, Finzi A, Lewis GK, Pazgier M. Gohain N, et al. Among authors: tolbert wd. Sci Rep. 2016 Nov 9;6:36685. doi: 10.1038/srep36685. Sci Rep. 2016. PMID: 27827447 Free PMC article.

6

Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region.

Tolbert WD, Gohain N, Alsahafi N, Van V, Orlandi C, Ding S, Martin L, Finzi A, Lewis GK, Ray K, Pazgier M. Tolbert WD, et al. Structure. 2017 Nov 7;25(11):1719-1731.e4. doi: 10.1016/j.str.2017.09.009. Epub 2017 Oct 19. Structure. 2017. PMID: 29056481 Free PMC article.

7

Two Families of Env Antibodies Efficiently Engage Fc-Gamma Receptors and Eliminate HIV-1-Infected Cells.

Anand SP, Prévost J, Baril S, Richard J, Medjahed H, Chapleau JP, Tolbert WD, Kirk S, Smith AB 3rd, Wines BD, Kent SJ, Hogarth PM, Parsons MS, Pazgier M, Finzi A. Anand SP, et al. Among authors: tolbert wd. J Virol. 2019 Jan 17;93(3):e01823-18. doi: 10.1128/JVI.01823-18. Print 2019 Feb 1. J Virol. 2019. PMID: 30429344 Free PMC article.

8

Structural Basis for Epitopes in the gp120 Cluster A Region that Invokes Potent Effector Cell Activity.

Tolbert WD, Sherburn RT, Van V, Pazgier M. Tolbert WD, et al. Viruses. 2019 Jan 16;11(1):69. doi: 10.3390/v11010069. Viruses. 2019. PMID: 30654465 Free PMC article. Review.

9

Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env.

Anand SP, Grover JR, Tolbert WD, Prévost J, Richard J, Ding S, Baril S, Medjahed H, Evans DT, Pazgier M, Mothes W, Finzi A. Anand SP, et al. Among authors: tolbert wd. J Virol. 2019 May 15;93(11):e00293-19. doi: 10.1128/JVI.00293-19. Print 2019 Jun 1. J Virol. 2019. PMID: 30894474 Free PMC article.

10

From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.

Tolbert WD, Subedi GP, Gohain N, Lewis GK, Patel KR, Barb AW, Pazgier M. Tolbert WD, et al. MAbs. 2019 May/Jun;11(4):709-724. doi: 10.1080/19420862.2019.1589852. Epub 2019 Apr 2. MAbs. 2019. PMID: 30939981 Free PMC article.

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