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Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression.
Wall MJ, Hill E, Huckstepp R, Barkan K, Deganutti G, Leuenberger M, Preti B, Winfield I, Carvalho S, Suchankova A, Wei H, Safitri D, Huang X, Imlach W, La Mache C, Dean E, Hume C, Hayward S, Oliver J, Zhao FY, Spanswick D, Reynolds CA, Lochner M, Ladds G, Frenguelli BG. Wall MJ, et al. Among authors: suchankova a. Nat Commun. 2022 Jul 18;13(1):4150. doi: 10.1038/s41467-022-31652-2. Nat Commun. 2022. PMID: 35851064 Free PMC article.
Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure-Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.
Stampelou M, Suchankova A, Tzortzini E, Dhingra L, Barkan K, Lougiakis N, Marakos P, Pouli N, Ladds G, Kolocouris A. Stampelou M, et al. Among authors: suchankova a. J Med Chem. 2022 Oct 13;65(19):13305-13327. doi: 10.1021/acs.jmedchem.2c01123. Epub 2022 Sep 29. J Med Chem. 2022. PMID: 36173355
Higher predation risk for insect prey at low latitudes and elevations.
Roslin T, Hardwick B, Novotny V, Petry WK, Andrew NR, Asmus A, Barrio IC, Basset Y, Boesing AL, Bonebrake TC, Cameron EK, Dáttilo W, Donoso DA, Drozd P, Gray CL, Hik DS, Hill SJ, Hopkins T, Huang S, Koane B, Laird-Hopkins B, Laukkanen L, Lewis OT, Milne S, Mwesige I, Nakamura A, Nell CS, Nichols E, Prokurat A, Sam K, Schmidt NM, Slade A, Slade V, Suchanková A, Teder T, van Nouhuys S, Vandvik V, Weissflog A, Zhukovich V, Slade EM. Roslin T, et al. Among authors: suchankova a. Science. 2017 May 19;356(6339):742-744. doi: 10.1126/science.aaj1631. Science. 2017. PMID: 28522532 Free article.
38 results