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High-level dolutegravir resistance can emerge rapidly from few variants and spread by recombination: implications for integrase strand transfer inhibitor salvage therapy.
Huik K, Hill S, George J, Pau A, Kuriakose S, Lange CM, Dee N, Stoll P, Khan M, Rehman T, Rehm CA, Dewar R, Grossman Z, Maldarelli F. Huik K, et al. Among authors: khan m. AIDS. 2022 Nov 1;36(13):1835-1840. doi: 10.1097/QAD.0000000000003288. Epub 2022 Jul 9. AIDS. 2022. PMID: 35848510 Free PMC article.
Rapid Development of High-Level Resistance to Dolutegravir With Emergence of T97A Mutation in 2 Treatment-Experienced Individuals With Baseline Partial Sensitivity to Dolutegravir.
George JM, Kuriakose SS, Dee N, Stoll P, Lalani T, Dewar R, Khan MA, Rehman MT, Grossman Z, Maldarelli F, Pau AK. George JM, et al. Among authors: khan ma. Open Forum Infect Dis. 2018 Sep 8;5(10):ofy221. doi: 10.1093/ofid/ofy221. eCollection 2018 Oct. Open Forum Infect Dis. 2018. PMID: 30568974 Free PMC article.
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