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Functional Parameters Derived from Magnetic Resonance Imaging Reflect Vascular Morphology in Preclinical Tumors and in Human Liver Metastases.
Kannan P, Kretzschmar WW, Winter H, Warren D, Bates R, Allen PD, Syed N, Irving B, Papiez BW, Kaeppler J, Markelc B, Kinchesh P, Gilchrist S, Smart S, Schnabel JA, Maughan T, Harris AL, Muschel RJ, Partridge M, Sharma RA, Kersemans V. Kannan P, et al. Clin Cancer Res. 2018 Oct 1;24(19):4694-4704. doi: 10.1158/1078-0432.CCR-18-0033. Epub 2018 Jun 29. Clin Cancer Res. 2018. PMID: 29959141 Free PMC article.
A lineage-tracing tool to map the fate of hypoxic tumour cells.
Vermeer JAF, Ient J, Markelc B, Kaeppler J, Barbeau LMO, Groot AJ, Muschel RJ, Vooijs MA. Vermeer JAF, et al. Dis Model Mech. 2020 Jul 30;13(7):dmm044768. doi: 10.1242/dmm.044768. Dis Model Mech. 2020. PMID: 32571767 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34004996
Multiscale topology characterizes dynamic tumor vascular networks.
Stolz BJ, Kaeppler J, Markelc B, Braun F, Lipsmeier F, Muschel RJ, Byrne HM, Harrington HA. Stolz BJ, et al. Sci Adv. 2022 Jun 10;8(23):eabm2456. doi: 10.1126/sciadv.abm2456. Epub 2022 Jun 10. Sci Adv. 2022. PMID: 35687679 Free PMC article.
Abnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation.
Bernabeu MO, Köry J, Grogan JA, Markelc B, Beardo A, d'Avezac M, Enjalbert R, Kaeppler J, Daly N, Hetherington J, Krüger T, Maini PK, Pitt-Francis JM, Muschel RJ, Alarcón T, Byrne HM. Bernabeu MO, et al. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):27811-27819. doi: 10.1073/pnas.2007770117. Epub 2020 Oct 27. Proc Natl Acad Sci U S A. 2020. PMID: 33109723 Free PMC article.