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Transcriptional profiles predict treatment outcome in patients with tuberculosis and diabetes at diagnosis and at two weeks after initiation of anti-tuberculosis treatment.
van Doorn CLR, Eckold C, Ronacher K, Ruslami R, van Veen S, Lee JS, Kumar V, Kerry-Barnard S, Malherbe ST, Kleynhans L, Stanley K, Hill PC, Joosten SA, van Crevel R, Wijmenga C, Critchley JA, Walzl G, Alisjahbana B, Haks MC, Dockrell HM, Ottenhoff THM, Vianello E, Cliff JM; TANDEM Consortium. van Doorn CLR, et al. Among authors: kumar v. EBioMedicine. 2022 Aug;82:104173. doi: 10.1016/j.ebiom.2022.104173. Epub 2022 Jul 15. EBioMedicine. 2022. PMID: 35841871 Free PMC article.
Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.
Buffen K, Oosting M, Quintin J, Ng A, Kleinnijenhuis J, Kumar V, van de Vosse E, Wijmenga C, van Crevel R, Oosterwijk E, Grotenhuis AJ, Vermeulen SH, Kiemeney LA, van de Veerdonk FL, Chamilos G, Xavier RJ, van der Meer JW, Netea MG, Joosten LA. Buffen K, et al. Among authors: kumar v. PLoS Pathog. 2014 Oct 30;10(10):e1004485. doi: 10.1371/journal.ppat.1004485. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25356988 Free PMC article.
GWAS as a Driver of Gene Discovery in Cardiometabolic Diseases.
Atanasovska B, Kumar V, Fu J, Wijmenga C, Hofker MH. Atanasovska B, et al. Among authors: kumar v. Trends Endocrinol Metab. 2015 Dec;26(12):722-732. doi: 10.1016/j.tem.2015.10.004. Epub 2015 Nov 18. Trends Endocrinol Metab. 2015. PMID: 26596674 Review.
Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence against Mycobacterium tuberculosis in human and murine cells.
Lachmandas E, Beigier-Bompadre M, Cheng SC, Kumar V, van Laarhoven A, Wang X, Ammerdorffer A, Boutens L, de Jong D, Kanneganti TD, Gresnigt MS, Ottenhoff TH, Joosten LA, Stienstra R, Wijmenga C, Kaufmann SH, van Crevel R, Netea MG. Lachmandas E, et al. Among authors: kumar v. Eur J Immunol. 2016 Nov;46(11):2574-2586. doi: 10.1002/eji.201546259. Epub 2016 Sep 27. Eur J Immunol. 2016. PMID: 27624090 Free PMC article.
Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study.
van Laarhoven A, Dian S, Aguirre-Gamboa R, Avila-Pacheco J, Ricaño-Ponce I, Ruesen C, Annisa J, Koeken VACM, Chaidir L, Li Y, Achmad TH, Joosten LAB, Notebaart RA, Ruslami R, Netea MG, Verbeek MM, Alisjahbana B, Kumar V, Clish CB, Ganiem AR, van Crevel R. van Laarhoven A, et al. Among authors: kumar v. Lancet Infect Dis. 2018 May;18(5):526-535. doi: 10.1016/S1473-3099(18)30053-7. Epub 2018 Feb 3. Lancet Infect Dis. 2018. PMID: 29395996
Tissue Metabolic Changes Drive Cytokine Responses to Mycobacterium tuberculosis.
Lachmandas E, Rios-Miguel AB, Koeken VACM, van der Pasch E, Kumar V, Matzaraki V, Li Y, Oosting M, Joosten LAB, Notebaart RA, Noursadeghi M, Netea MG, van Crevel R, Pollara G. Lachmandas E, et al. Among authors: kumar v. J Infect Dis. 2018 Jun 5;218(1):165-170. doi: 10.1093/infdis/jiy173. J Infect Dis. 2018. PMID: 29618104 Free PMC article.
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