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A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals.
Alugubelli YR, Geng ZZ, Yang KS, Shaabani N, Khatua K, Ma XR, Vatansever EC, Cho CC, Ma Y, Xiao J, Blankenship LR, Yu G, Sankaran B, Li P, Allen R, Ji H, Xu S, Liu WR. Alugubelli YR, et al. Among authors: sankaran b. Eur J Med Chem. 2022 Oct 5;240:114596. doi: 10.1016/j.ejmech.2022.114596. Epub 2022 Jul 8. Eur J Med Chem. 2022. PMID: 35839690 Free PMC article.
A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors.
Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR. Yang KS, et al. Among authors: sankaran b. bioRxiv [Preprint]. 2020 Jul 28:2020.07.28.223784. doi: 10.1101/2020.07.28.223784. bioRxiv. 2020. PMID: 32766582 Free PMC article. Updated. Preprint.
The Structural Basis of IRF-3 Activation upon Phosphorylation.
Jing T, Zhao B, Xu P, Gao X, Chi L, Han H, Sankaran B, Li P. Jing T, et al. Among authors: sankaran b. J Immunol. 2020 Oct 1;205(7):1886-1896. doi: 10.4049/jimmunol.2000026. Epub 2020 Aug 21. J Immunol. 2020. PMID: 32826280 Free PMC article.
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR. Yang KS, et al. Among authors: sankaran b. ChemMedChem. 2021 Mar 18;16(6):942-948. doi: 10.1002/cmdc.202000924. Epub 2020 Dec 10. ChemMedChem. 2021. PMID: 33283984 Free PMC article.
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors.
Chamakuri S, Lu S, Ucisik MN, Bohren KM, Chen YC, Du HC, Faver JC, Jimmidi R, Li F, Li JY, Nyshadham P, Palmer SS, Pollet J, Qin X, Ronca SE, Sankaran B, Sharma KL, Tan Z, Versteeg L, Yu Z, Matzuk MM, Palzkill T, Young DW. Chamakuri S, et al. Among authors: sankaran b. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2111172118. doi: 10.1073/pnas.2111172118. Proc Natl Acad Sci U S A. 2021. PMID: 34426525 Free PMC article.
A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals.
Ma Y, Yang KS, Geng ZZ, Alugubelli YR, Shaabani N, Vatansever EC, Ma XR, Cho CC, Khatua K, Xiao J, Blankenship LR, Yu G, Sankaran B, Li P, Allen R, Ji H, Xu S, Liu WR. Ma Y, et al. Among authors: sankaran b. Eur J Med Chem. 2022 Oct 5;240:114570. doi: 10.1016/j.ejmech.2022.114570. Epub 2022 Jun 27. Eur J Med Chem. 2022. PMID: 35779291 Free PMC article.
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors.
Jimmidi R, Chamakuri S, Lu S, Ucisik MN, Chen PJ, Bohren KM, Moghadasi SA, Versteeg L, Nnabuife C, Li JY, Qin X, Chen YC, Faver JC, Nyshadham P, Sharma KL, Sankaran B, Judge A, Yu Z, Li F, Pollet J, Harris RS, Matzuk MM, Palzkill T, Young DW. Jimmidi R, et al. Among authors: sankaran b. Commun Chem. 2023 Aug 4;6(1):164. doi: 10.1038/s42004-023-00961-y. Commun Chem. 2023. PMID: 37542196 Free PMC article.
229 results