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Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression.
Zagozewski J, Borlase S, Guppy BJ, Coudière-Morrison L, Shahriary GM, Gordon V, Liang L, Cheng S, Porter CJ, Kelley R, Hawkins C, Chan JA, Liang Y, Gong J, Nör C, Saulnier O, Wechsler-Reya RJ, Ramaswamy V, Werbowetski-Ogilvie TE. Zagozewski J, et al. Among authors: liang l, liang y. Commun Biol. 2022 Jul 14;5(1):697. doi: 10.1038/s42003-022-03654-9. Commun Biol. 2022. PMID: 35835937 Free PMC article.
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler.
Bergholtz H, Carter JM, Cesano A, Cheang MCU, Church SE, Divakar P, Fuhrman CA, Goel S, Gong J, Guerriero JL, Hoang ML, Hwang ES, Kuasne H, Lee J, Liang Y, Mittendorf EA, Perez J, Prat A, Pusztai L, Reeves JW, Riazalhosseini Y, Richer JK, Sahin Ö, Sato H, Schlam I, Sørlie T, Stover DG, Swain SM, Swarbrick A, Thompson EA, Tolaney SM, Warren SE, On Behalf Of The GeoMx Breast Cancer Consortium. Bergholtz H, et al. Among authors: liang y. Cancers (Basel). 2021 Sep 4;13(17):4456. doi: 10.3390/cancers13174456. Cancers (Basel). 2021. PMID: 34503266 Free PMC article.
Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy.
Robinson MH, Villa NY, Jaye DL, Nooka AK, Duffy A, McCachren SS, Manalo J, Switchenko JM, Barnes S, Potdar S, Azeem MI, Horvat AA, Parihar VC, Gong J, Liang Y, Smith GH, Gupta VA, Boise LH, Kaufman JL, Hofmeister CC, Joseph NS, Lonial S, Dhodapkar KM, Dhodapkar MV. Robinson MH, et al. Among authors: liang y. J Clin Invest. 2023 Aug 1;133(15):e167629. doi: 10.1172/JCI167629. J Clin Invest. 2023. PMID: 37526080 Free PMC article.
Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling.
Zimmerman SM, Fropf R, Kulasekara BR, Griswold M, Appelbe O, Bahrami A, Boykin R, Buhr DL, Fuhrman K, Hoang ML, Huynh Q, Isgur L, Klock A, Kutchma A, Lasley AE, Liang Y, McKay-Fleisch J, Nelson JS, Nguyen K, Piazza E, Rininger A, Zollinger DR, Rhodes M, Beechem JM. Zimmerman SM, et al. Among authors: liang y. Genome Res. 2022 Oct;32(10):1892-1905. doi: 10.1101/gr.276206.121. Epub 2022 Sep 13. Genome Res. 2022. PMID: 36100434 Free PMC article.
Novel intragraft regulatory lymphoid structures in kidney allograft tolerance.
Rosales IA, Yang C, Farkash EA, Ashry T, Ge J, Aljabban I, Ayyar A, Ndishabandi D, White R, Gildner E, Gong J, Liang Y, Lakkis FG, Nickeleit V, Russell PS, Madsen JC, Alessandrini A, Colvin RB. Rosales IA, et al. Among authors: liang y. Am J Transplant. 2022 Mar;22(3):705-716. doi: 10.1111/ajt.16880. Epub 2021 Dec 3. Am J Transplant. 2022. PMID: 34726836 Free article.
Dissecting the immune landscape of tumor draining lymph nodes in melanoma with high-plex spatially resolved protein detection.
Beasley GM, Therien AD, Holl EK, Al-Rohil R, Selim MA, Farrow NE, Pan L, Haynes P, Liang Y, Tyler DS, Hanks BA, Nair SK. Beasley GM, et al. Among authors: liang y. Cancer Immunol Immunother. 2021 Feb;70(2):475-483. doi: 10.1007/s00262-020-02698-2. Epub 2020 Aug 19. Cancer Immunol Immunother. 2021. PMID: 32814992 Free PMC article.
In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting.
Tu WJ, Melino M, Dunn J, McCuaig RD, Bielefeldt-Ohmann H, Tsimbalyuk S, Forwood JK, Ahuja T, Vandermeide J, Tan X, Tran M, Nguyen Q, Zhang L, Nam A, Pan L, Liang Y, Smith C, Lineburg K, Nguyen TH, Sng JDJ, Tong ZWM, Chew KY, Short KR, Le Grand R, Seddiki N, Rao S. Tu WJ, et al. Among authors: liang y. Nat Commun. 2023 Jun 27;14(1):3680. doi: 10.1038/s41467-023-39341-4. Nat Commun. 2023. PMID: 37369668 Free PMC article.
Multiplex digital spatial profiling of proteins and RNA in fixed tissue.
Merritt CR, Ong GT, Church SE, Barker K, Danaher P, Geiss G, Hoang M, Jung J, Liang Y, McKay-Fleisch J, Nguyen K, Norgaard Z, Sorg K, Sprague I, Warren C, Warren S, Webster PJ, Zhou Z, Zollinger DR, Dunaway DL, Mills GB, Beechem JM. Merritt CR, et al. Among authors: liang y. Nat Biotechnol. 2020 May;38(5):586-599. doi: 10.1038/s41587-020-0472-9. Epub 2020 May 11. Nat Biotechnol. 2020. PMID: 32393914
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