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Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.
Titus HE, Xu H, Robinson AP, Patel PA, Chen Y, Fantini D, Eaton V, Karl M, Garrison ED, Rose IVL, Chiang MY, Podojil JR, Balabanov R, Liddelow SA, Miller RH, Popko B, Miller SD. Titus HE, et al. Among authors: liddelow sa. Glia. 2022 Oct;70(10):1950-1970. doi: 10.1002/glia.24231. Epub 2022 Jul 9. Glia. 2022. PMID: 35809238 Free PMC article.
Activated microglia drive demyelination via CSF1R signaling.
Marzan DE, Brügger-Verdon V, West BL, Liddelow S, Samanta J, Salzer JL. Marzan DE, et al. Glia. 2021 Jun;69(6):1583-1604. doi: 10.1002/glia.23980. Epub 2021 Feb 23. Glia. 2021. PMID: 33620118 Free PMC article.
Neuroinflammatory astrocyte subtypes in the mouse brain.
Hasel P, Rose IVL, Sadick JS, Kim RD, Liddelow SA. Hasel P, et al. Among authors: liddelow sa. Nat Neurosci. 2021 Oct;24(10):1475-1487. doi: 10.1038/s41593-021-00905-6. Epub 2021 Aug 19. Nat Neurosci. 2021. PMID: 34413515
CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes.
Barbar L, Jain T, Zimmer M, Kruglikov I, Sadick JS, Wang M, Kalpana K, Rose IVL, Burstein SR, Rusielewicz T, Nijsure M, Guttenplan KA, di Domenico A, Croft G, Zhang B, Nobuta H, Hébert JM, Liddelow SA, Fossati V. Barbar L, et al. Among authors: liddelow sa. Neuron. 2020 Aug 5;107(3):436-453.e12. doi: 10.1016/j.neuron.2020.05.014. Epub 2020 Jun 1. Neuron. 2020. PMID: 32485136 Free PMC article.
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time.
Prakash P, Jethava KP, Korte N, Izquierdo P, Favuzzi E, Rose IVL, Guttenplan KA, Manchanda P, Dutta S, Rochet JC, Fishell G, Liddelow SA, Attwell D, Chopra G. Prakash P, et al. Among authors: liddelow sa. Chem Sci. 2021 Jul 21;12(32):10901-10918. doi: 10.1039/d1sc03486c. eCollection 2021 Aug 18. Chem Sci. 2021. PMID: 34476070 Free PMC article.
Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis.
Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galán-Echevarría F, Karz A, Argibay D, Von Itter R, Floristán A, Baptiste G, Eskow NM, Tranos JA, Chen J, Vega Y Saenz de Miera EC, Call M, Rogers R, Jour G, Wadghiri YZ, Osman I, Li YM, Mathews P, DeMattos RB, Ueberheide B, Ruggles KV, Liddelow SA, Schneider RJ, Hernando E. Kleffman K, et al. Among authors: liddelow sa. Cancer Discov. 2022 May 2;12(5):1314-1335. doi: 10.1158/2159-8290.CD-21-1006. Cancer Discov. 2022. PMID: 35262173 Free PMC article.
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