Puigserver P - Search Results

1

Mechanisms of mitochondrial respiratory adaptation.

Bennett CF, Latorre-Muro P, Puigserver P. Bennett CF, et al. Among authors: puigserver p. Nat Rev Mol Cell Biol. 2022 Dec;23(12):817-835. doi: 10.1038/s41580-022-00506-6. Epub 2022 Jul 8. Nat Rev Mol Cell Biol. 2022. PMID: 35804199 Free PMC article. Review.

2

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.

Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, Troy A, Cinti S, Lowell B, Scarpulla RC, Spiegelman BM. Wu Z, et al. Among authors: puigserver p. Cell. 1999 Jul 9;98(1):115-24. doi: 10.1016/S0092-8674(00)80611-X. Cell. 1999. PMID: 10412986 Free article.

3

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.

Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P. Cunningham JT, et al. Among authors: puigserver p. Nature. 2007 Nov 29;450(7170):736-40. doi: 10.1038/nature06322. Nature. 2007. PMID: 18046414

4

Foxo1 integrates insulin signaling with mitochondrial function in the liver.

Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF. Cheng Z, et al. Among authors: puigserver p. Nat Med. 2009 Nov;15(11):1307-11. doi: 10.1038/nm.2049. Epub 2009 Oct 18. Nat Med. 2009. PMID: 19838201 Free PMC article.

5

Clk2 and B56β mediate insulin-regulated assembly of the PP2A phosphatase holoenzyme complex on Akt.

Rodgers JT, Vogel RO, Puigserver P. Rodgers JT, et al. Among authors: puigserver p. Mol Cell. 2011 Feb 18;41(4):471-9. doi: 10.1016/j.molcel.2011.02.007. Mol Cell. 2011. PMID: 21329884 Free PMC article.

6

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

Gerhart-Hines Z, Dominy JE Jr, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. Gerhart-Hines Z, et al. Among authors: puigserver p. Mol Cell. 2011 Dec 23;44(6):851-63. doi: 10.1016/j.molcel.2011.12.005. Mol Cell. 2011. PMID: 22195961 Free PMC article.

7

Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle.

Blättler SM, Verdeguer F, Liesa M, Cunningham JT, Vogel RO, Chim H, Liu H, Romanino K, Shirihai OS, Vazquez F, Rüegg MA, Shi Y, Puigserver P. Blättler SM, et al. Among authors: puigserver p. Mol Cell Biol. 2012 Aug;32(16):3333-46. doi: 10.1128/MCB.00337-12. Epub 2012 Jun 18. Mol Cell Biol. 2012. PMID: 22711985 Free PMC article.

8

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.

Vazquez F, Lim JH, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, Puigserver P. Vazquez F, et al. Among authors: puigserver p. Cancer Cell. 2013 Mar 18;23(3):287-301. doi: 10.1016/j.ccr.2012.11.020. Epub 2013 Feb 14. Cancer Cell. 2013. PMID: 23416000 Free PMC article.

9

A PGC1α-mediated transcriptional axis suppresses melanoma metastasis.

Luo C, Lim JH, Lee Y, Granter SR, Thomas A, Vazquez F, Widlund HR, Puigserver P. Luo C, et al. Among authors: puigserver p. Nature. 2016 Sep 15;537(7620):422-426. doi: 10.1038/nature19347. Epub 2016 Aug 31. Nature. 2016. PMID: 27580028 Free PMC article.

10

Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations.

Barrow JJ, Balsa E, Verdeguer F, Tavares CD, Soustek MS, Hollingsworth LR 4th, Jedrychowski M, Vogel R, Paulo JA, Smeitink J, Gygi SP, Doench J, Root DE, Puigserver P. Barrow JJ, et al. Among authors: puigserver p. Mol Cell. 2016 Oct 6;64(1):163-175. doi: 10.1016/j.molcel.2016.08.023. Epub 2016 Sep 22. Mol Cell. 2016. PMID: 27666594 Free PMC article.

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