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GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia.
Liu L, Patnana PK, Xie X, Frank D, Nimmagadda SC, Su M, Zhang D, Koenig T, Rosenbauer F, Liebmann M, Klotz L, Xu W, Vorwerk J, Neumann F, Hüve J, Unger A, Okun JG, Opalka B, Khandanpour C. Liu L, et al. Among authors: opalka b. Leukemia. 2022 Sep;36(9):2196-2207. doi: 10.1038/s41375-022-01635-9. Epub 2022 Jul 8. Leukemia. 2022. PMID: 35804097 Free PMC article.
Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome.
Thivakaran A, Botezatu L, Hönes JM, Schütte J, Vassen L, Al-Matary YS, Patnana P, Zeller A, Heuser M, Thol F, Gabdoulline R, Olberding N, Frank D, Suslo M, Köster R, Lennartz K, Görgens A, Giebel B, Opalka B, Dührsen U, Khandanpour C. Thivakaran A, et al. Among authors: opalka b. Haematologica. 2018 Apr;103(4):614-625. doi: 10.3324/haematol.2017.167288. Epub 2018 Jan 11. Haematologica. 2018. PMID: 29326122 Free PMC article.
Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
Ahmed HMM, Nimmagadda SC, Al-Matary YS, Fiori M, May T, Frank D, Patnana PK, Récher C, Schliemann C, Mikesch JH, Koenig T, Rosenbauer F, Hartmann W, Tuckermann J, Dührsen U, Lanying W, Dugas M, Opalka B, Lenz G, Khandanpour C. Ahmed HMM, et al. Among authors: opalka b. Br J Haematol. 2022 Feb;196(4):995-1006. doi: 10.1111/bjh.17940. Epub 2021 Nov 18. Br J Haematol. 2022. PMID: 34792186
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner.
Al-Matary YS, Botezatu L, Opalka B, Hönes JM, Lams RF, Thivakaran A, Schütte J, Köster R, Lennartz K, Schroeder T, Haas R, Dührsen U, Khandanpour C. Al-Matary YS, et al. Among authors: opalka b. Haematologica. 2016 Oct;101(10):1216-1227. doi: 10.3324/haematol.2016.143180. Epub 2016 Jul 7. Haematologica. 2016. PMID: 27390361 Free PMC article.
GFI1(36N) as a therapeutic and prognostic marker for myelodysplastic syndrome.
Botezatu L, Michel LC, Makishima H, Schroeder T, Germing U, Haas R, van der Reijden B, Marneth AE, Bergevoet SM, Jansen JH, Przychodzen B, Wlodarski M, Niemeyer C, Platzbecker U, Ehninger G, Unnikrishnan A, Beck D, Pimanda J, Hellström-Lindberg E, Malcovati L, Boultwood J, Pellagatti A, Papaemmanuil E, Le Coutre P, Kaeda J, Opalka B, Möröy T, Dührsen U, Maciejewski J, Khandanpour C. Botezatu L, et al. Among authors: opalka b. Exp Hematol. 2016 Jul;44(7):590-595.e1. doi: 10.1016/j.exphem.2016.04.001. Epub 2016 Apr 11. Exp Hematol. 2016. PMID: 27080012 Free PMC article.
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