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Optimized Pyridazinone Nutrient Channel Inhibitors Are Potent and Specific Antimalarial Leads.
Butler MM, Waidyarachchi SL, Shao J, Nguyen ST, Ding X, Cardinale SC, Morin LR, Kwasny SM, Ito M, Gezelle J, Jiménez-Díaz MB, Angulo-Barturen I, Jacobs RT, Burrows JN, Aron ZD, Bowlin TL, Desai SA. Butler MM, et al. Among authors: ding x. Mol Pharmacol. 2022 Sep;102(3):172-182. doi: 10.1124/molpharm.122.000549. Epub 2022 Jul 7. Mol Pharmacol. 2022. PMID: 35798366 Free PMC article.
Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: synthesis and SAR of novel analogs of MBX 1066 and MBX 1090.
Williams JD, Nguyen ST, Gu S, Ding X, Butler MM, Tashjian TF, Opperman TJ, Panchal RG, Bavari S, Peet NP, Moir DT, Bowlin TL. Williams JD, et al. Among authors: ding x. Bioorg Med Chem. 2013 Dec 15;21(24):7790-806. doi: 10.1016/j.bmc.2013.10.014. Epub 2013 Oct 25. Bioorg Med Chem. 2013. PMID: 24239389 Free PMC article.
Synthesis and antibacterial evaluation of new, unsymmetrical triaryl bisamidine compounds.
Nguyen ST, Williams JD, Butler MM, Ding X, Mills DM, Tashjian TF, Panchal RG, Weir SK, Moon C, Kim HO, Marsden JA, Peet NP, Bowlin TL. Nguyen ST, et al. Among authors: ding x. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3366-72. doi: 10.1016/j.bmcl.2014.05.094. Epub 2014 Jun 12. Bioorg Med Chem Lett. 2014. PMID: 24969013 Free PMC article.
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