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Swarms of chemically modified antiviral siRNA targeting herpes simplex virus infection in human corneal epithelial cells.
PLoS Pathog. 2022 Jul 6;18(7):e1010688. doi: 10.1371/journal.ppat.1010688. eCollection 2022 Jul.
PLoS Pathog. 2022.
PMID: 35793357
Free PMC article.
Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity.
Levanova AA, Kalke KM, Lund LM, Sipari N, Sadeghi M, Nyman MC, Paavilainen H, Hukkanen V, Poranen MM.
Levanova AA, et al.
Antiviral Res. 2020 Oct;182:104916. doi: 10.1016/j.antiviral.2020.104916. Epub 2020 Aug 13.
Antiviral Res. 2020.
PMID: 32798603
Free PMC article.
Item in Clipboard
Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity.
Kalke K, Lehtinen J, Gnjatovic J, Lund LM, Nyman MC, Paavilainen H, Orpana J, Lasanen T, Frejborg F, Levanova AA, Vuorinen T, Poranen MM, Hukkanen V.
Kalke K, et al. Among authors: levanova aa.
Viruses. 2020 Dec 13;12(12):1434. doi: 10.3390/v12121434.
Viruses. 2020.
PMID: 33322225
Free PMC article.
Item in Clipboard
RNA-Dependent RNA Polymerase from Heterobasidion RNA Virus 6 Is an Active Replicase In Vitro.
Levanova AA, Vainio EJ, Hantula J, Poranen MM.
Levanova AA, et al.
Viruses. 2021 Aug 31;13(9):1738. doi: 10.3390/v13091738.
Viruses. 2021.
PMID: 34578320
Free PMC article.
Item in Clipboard
Native RNA Purification Method for Small RNA Molecules Based on Asymmetrical Flow Field-Flow Fractionation.
Levanova AA, Lampi M, Kalke K, Hukkanen V, Poranen MM, Eskelin K.
Levanova AA, et al.
Pharmaceuticals (Basel). 2022 Feb 21;15(2):261. doi: 10.3390/ph15020261.
Pharmaceuticals (Basel). 2022.
PMID: 35215370
Free PMC article.
Item in Clipboard
Application of steric exclusion chromatography on monoliths for separation and purification of RNA molecules.
Levanova A, Poranen MM.
Levanova A, et al.
J Chromatogr A. 2018 Nov 2;1574:50-59. doi: 10.1016/j.chroma.2018.08.063. Epub 2018 Aug 31.
J Chromatogr A. 2018.
PMID: 30195858
Free article.
Item in Clipboard
RNA Interference as a Prospective Tool for the Control of Human Viral Infections.
Levanova A, Poranen MM.
Levanova A, et al.
Front Microbiol. 2018 Sep 11;9:2151. doi: 10.3389/fmicb.2018.02151. eCollection 2018.
Front Microbiol. 2018.
PMID: 30254624
Free PMC article.
Review.
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Utilization of Bacteriophage phi6 for the Production of High-Quality Double-Stranded RNA Molecules.
Levanova AA, Poranen MM.
Levanova AA, et al.
Viruses. 2024 Jan 22;16(1):166. doi: 10.3390/v16010166.
Viruses. 2024.
PMID: 38275976
Free PMC article.
Review.
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