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Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs.
Augustynek B, Gyimesi G, Dernič J, Sallinger M, Albano G, Klesse GJ, Kandasamy P, Grabmayr H, Frischauf I, Fuster DG, Peinelt C, Hediger MA, Bhardwaj R. Augustynek B, et al. Among authors: sallinger m. Cell Calcium. 2022 Jul;105:102616. doi: 10.1016/j.ceca.2022.102616. Epub 2022 Jun 22. Cell Calcium. 2022. PMID: 35792401 Free article.
Blockage of Store-Operated Ca2+ Influx by Synta66 is Mediated by Direct Inhibition of the Ca2+ Selective Orai1 Pore.
Waldherr L, Tiffner A, Mishra D, Sallinger M, Schober R, Frischauf I, Schmidt T, Handl V, Sagmeister P, Köckinger M, Derler I, Üçal M, Bonhenry D, Patz S, Schindl R. Waldherr L, et al. Among authors: sallinger m. Cancers (Basel). 2020 Oct 6;12(10):2876. doi: 10.3390/cancers12102876. Cancers (Basel). 2020. PMID: 33036292 Free PMC article.
CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.
Tiffner A, Schober R, Höglinger C, Bonhenry D, Pandey S, Lunz V, Sallinger M, Frischauf I, Fahrner M, Lindinger S, Maltan L, Berlansky S, Stadlbauer M, Schindl R, Ettrich R, Romanin C, Derler I. Tiffner A, et al. Among authors: sallinger m. J Biol Chem. 2021 Jan-Jun;296:100224. doi: 10.1074/jbc.RA120.015548. Epub 2020 Dec 29. J Biol Chem. 2021. PMID: 33361160 Free PMC article.
Orai channels: key players in Ca2+ homeostasis.
Sallinger M, Berlansky S, Frischauf I. Sallinger M, et al. Curr Opin Physiol. 2020 Oct;17:42-49. doi: 10.1016/j.cophys.2020.06.006. Epub 2020 Jun 29. Curr Opin Physiol. 2020. PMID: 33409426 Free PMC article.
Orai1 Boosts SK3 Channel Activation.
Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Höglinger C, Fahrner M, Lunz V, Maltan L, Frischauf I, Krivic D, Bhardwaj R, Schindl R, Hediger MA, Derler I. Tiffner A, et al. Among authors: sallinger m. Cancers (Basel). 2021 Dec 17;13(24):6357. doi: 10.3390/cancers13246357. Cancers (Basel). 2021. PMID: 34944977 Free PMC article.
16 results