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Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs.
Augustynek B, Gyimesi G, Dernič J, Sallinger M, Albano G, Klesse GJ, Kandasamy P, Grabmayr H, Frischauf I, Fuster DG, Peinelt C, Hediger MA, Bhardwaj R. Augustynek B, et al. Among authors: bhardwaj r. Cell Calcium. 2022 Jul;105:102616. doi: 10.1016/j.ceca.2022.102616. Epub 2022 Jun 22. Cell Calcium. 2022. PMID: 35792401 Free article.
Redox modulation of STIM-ORAI signaling.
Bhardwaj R, Hediger MA, Demaurex N. Bhardwaj R, et al. Cell Calcium. 2016 Aug;60(2):142-52. doi: 10.1016/j.ceca.2016.03.006. Epub 2016 Mar 19. Cell Calcium. 2016. PMID: 27041216 Free article. Review.
A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
Butorac C, Muik M, Derler I, Stadlbauer M, Lunz V, Krizova A, Lindinger S, Schober R, Frischauf I, Bhardwaj R, Hediger MA, Groschner K, Romanin C. Butorac C, et al. Among authors: bhardwaj r. Cell Calcium. 2019 May;79:57-67. doi: 10.1016/j.ceca.2019.02.009. Epub 2019 Feb 23. Cell Calcium. 2019. PMID: 30831274 Free article.
Photoswitchable Inhibitor of the Calcium Channel TRPV6.
Cunha MR, Bhardwaj R, Lindinger S, Butorac C, Romanin C, Hediger MA, Reymond JL. Cunha MR, et al. Among authors: bhardwaj r. ACS Med Chem Lett. 2019 Aug 2;10(9):1341-1345. doi: 10.1021/acsmedchemlett.9b00298. eCollection 2019 Sep 12. ACS Med Chem Lett. 2019. PMID: 31531207 Free PMC article.
Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells.
Schild A, Bhardwaj R, Wenger N, Tscherrig D, Kandasamy P, Dernič J, Baur R, Peinelt C, Hediger MA, Lochner M. Schild A, et al. Among authors: bhardwaj r. Int J Mol Sci. 2020 Aug 5;21(16):5604. doi: 10.3390/ijms21165604. Int J Mol Sci. 2020. PMID: 32764353 Free PMC article.
Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry.
Gibhardt CS, Cappello S, Bhardwaj R, Schober R, Kirsch SA, Bonilla Del Rio Z, Gahbauer S, Bochicchio A, Sumanska M, Ickes C, Stejerean-Todoran I, Mitkovski M, Alansary D, Zhang X, Revazian A, Fahrner M, Lunz V, Frischauf I, Luo T, Ezerina D, Messens J, Belousov VV, Hoth M, Böckmann RA, Hediger MA, Schindl R, Bogeski I. Gibhardt CS, et al. Among authors: bhardwaj r. Cell Rep. 2020 Oct 20;33(3):108292. doi: 10.1016/j.celrep.2020.108292. Cell Rep. 2020. PMID: 33086068 Free article.
881 results