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Monoclonal antibodies binding data for SARS-CoV-2 proteins.
Mishra N, Teyra J, Boytz R, Miersch S, Merritt TN, Cardarelli L, Gorelik M, Mihalic F, Jemth P, Davey RA, Sidhu SS, Leung DW, Amarasinghe GK. Mishra N, et al. Among authors: amarasinghe gk. Data Brief. 2022 Aug;43:108415. doi: 10.1016/j.dib.2022.108415. Epub 2022 Jun 24. Data Brief. 2022. PMID: 35789908 Free PMC article.
Ebolavirus VP35 is a multifunctional virulence factor.
Leung DW, Prins KC, Basler CF, Amarasinghe GK. Leung DW, et al. Among authors: amarasinghe gk. Virulence. 2010 Nov-Dec;1(6):526-31. doi: 10.4161/viru.1.6.12984. Epub 2010 Nov 1. Virulence. 2010. PMID: 21178490 Free PMC article.
Molecular mechanisms of viral inhibitors of RIG-I-like receptors.
Leung DW, Basler CF, Amarasinghe GK. Leung DW, et al. Among authors: amarasinghe gk. Trends Microbiol. 2012 Mar;20(3):139-46. doi: 10.1016/j.tim.2011.12.005. Epub 2012 Feb 8. Trends Microbiol. 2012. PMID: 22325030 Free PMC article. Review.
Aptamers in virology: recent advances and challenges.
Binning JM, Leung DW, Amarasinghe GK. Binning JM, et al. Among authors: amarasinghe gk. Front Microbiol. 2012 Feb 8;3:29. doi: 10.3389/fmicb.2012.00029. eCollection 2012. Front Microbiol. 2012. PMID: 22347221 Free PMC article.
Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.
Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK. Ramanan P, et al. Among authors: amarasinghe gk. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20661-6. doi: 10.1073/pnas.1213559109. Epub 2012 Nov 26. Proc Natl Acad Sci U S A. 2012. PMID: 23185024 Free PMC article.
Development of RNA aptamers targeting Ebola virus VP35.
Binning JM, Wang T, Luthra P, Shabman RS, Borek DM, Liu G, Xu W, Leung DW, Basler CF, Amarasinghe GK. Binning JM, et al. Among authors: amarasinghe gk. Biochemistry. 2013 Nov 26;52(47):8406-19. doi: 10.1021/bi400704d. Epub 2013 Nov 14. Biochemistry. 2013. PMID: 24067086 Free PMC article.
In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity.
Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, Amarasinghe GK. Brown CS, et al. Among authors: amarasinghe gk. J Mol Biol. 2014 May 15;426(10):2045-58. doi: 10.1016/j.jmb.2014.01.010. Epub 2014 Feb 1. J Mol Biol. 2014. PMID: 24495995 Free PMC article.
129 results